Results 241 to 250 of about 1,407,327 (308)

The IL-36 Cytokine Rheostat: Hierarchical Regulation of Epithelial-Immune Crosstalk and Precision Therapy in Psoriatic and Related Dermatoses. [PDF]

Clin Cosmet Investig Dermatol
Qiao ZY, Liu JH, Luo NN, Tang L, Ma WY, Cheng ZL, Hao PS.   +6 more
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Structural Analysis of Human LonP1 Protease Bound with the Native Substrate. [PDF]

Life (Basel)
Li M, Liu H, Zhang S, Gao Q, Li S, Wang J, Zhang K.   +6 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

3D Proteomics: Structural, Functional, Chemical and Biomarker Discovery Proteomics With LiP-MS. [PDF]

Mol Cell Proteomics
Elsässer F, de Souza N, Picotti P.
europepmc   +1 more source

Plant subtilases as key initiators of peptide ligand-receptor signaling. [PDF]

Plant J
Matsui S, Hirakawa Y.
europepmc   +1 more source

A Double-Edged Sword: Extracellular Serine Proteases as Facilitators of Infection and Mediators of Immunity. [PDF]

Molecules
Shagirova A, Allayarova M, Makhanova A, Bekturgan A, Burster T.   +4 more
europepmc   +1 more source

DiNovo enables high-coverage and high-confidence de novo peptide sequencing via mirror proteases and deep learning. [PDF]

Nat Commun
Cao Z, Peng X, Zhang D, Zhou P, Kang L, Chi H, Wu R, Cheng Z, Zhang Y, Dai J, Li Y, Yao L, Li X, He Y, Yang J, Wang H, Xu P, Fu Y.   +17 more
europepmc   +1 more source

Correction for Jaen Maisonet et al., Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7). [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Addendum: Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq. [PDF]

Nat Commun
Bottini S, Hamouda-Tekaya N, Mategot R, Zaragosi LE, Audebert S, Pisano S, Grandjean V, Mauduit C, Benahmed M, Barbry P, Repetto E, Trabucchi M.   +11 more
europepmc   +1 more source