Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan +17 more
wiley +1 more source
DiNovo enables high-coverage and high-confidence de novo peptide sequencing via mirror proteases and deep learning. [PDF]
Cao Z +17 more
europepmc +1 more source
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Microbial fermentation as a strategy for the abatement of peanut allergens. [PDF]
Yammoul Guzman N +2 more
europepmc +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Enemy's arsenal backfires: pathogen proteases detonate broad-spectrum plant immunity via engineered NLRs. [PDF]
Liu S, Jing Y, Chen J.
europepmc +1 more source
Integrating Vibrio natriegens for Photon Manipulation in Living Lighting Devices
Rationalization of genetic and material engineering tools has enabled the engineering of fluorescent Vibrio natriegens (V. natriegens) to fabricate straightforward, highly emissive and stable V. natriegens‐silicones color filters for the first red‐emitting bacteria‐hybrid light‐emitting diodes. This pinpoints V. natriegens as a high‐performance protein
Stephanie Willeit +6 more
wiley +1 more source
The Evolution, Oligomerization, Function, and Action Mechanism of α2-Macroglobulin. [PDF]
Xie W, Gao L, Deng H, Liu D, Pang Q.
europepmc +1 more source
Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed +9 more
wiley +1 more source
Thermolysin Versus Four Commercial Proteases in the Modification of Soy Protein Isolate: Structural, Functional, and Taste Characterization. [PDF]
Liu X, Yin J, Yin S, Chen P, Zhang B.
europepmc +1 more source

