Results 81 to 90 of about 327,704 (298)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Handling Regulated Data, Protected Health Information, and CUI

, 2017
Handling regulated government data, protected health information, and controlled unclassified ...
Shankar, Anurag
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

2015 protected health information data breach report

, 2015
The purpose of this study is to shed light on the problem of medical data loss—how it is disclosed, who is causing it and what can be done to combat it. This is a far-reaching problem that impacts not only organizations that are victims of these breaches,
Verizon
core  

“Whispers from the Wrist”: Wearable Health Monitoring Devices and Privacy Regulations in the U.S.: The Loopholes, the Challenges, and the Opportunities

Cryptography
The growth of wearable technology has enabled the collection of even more personalized information on individuals. New health-related devices marketed to consumers collect health information that might not fall under the traditional category of Protected
Asma Sifaoui, Matthew S. Eastin
doaj   +1 more source

Digital Health Data: A Comprehensive Review of Privacy and Security Risks and Some Recommendations [PDF]

Computer Science Journal of Moldova, 2016
In today’s world, health data are being produced in ever\-increasing amounts due to extensive use of medical devices generating data in digital form. These data are stored in diverse formats at different health information systems.
Shahidul Islam Khan, Abu Sayed Md. Latiful Hoque   +1 more
doaj  

Ensemble Approaches to Recognize Protected Health Information in Radiology Reports. [PDF]

J Digit Imaging, 2022
Horng H, Steinkamp J, Kahn CE, Cook TS.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Automatic de-identification of protected health information

, 2014
This paper presents an automatic de-identification system for Serbian, grounded on a rapid adaptation of the existing named entity recognition system. Based on a finite-state methodology and lexical resources, the system is designed to detect and replace
Krstev, Cvetana, Jaćimović, Jelena, Jelovac, Drago   +2 more
core