Results 201 to 210 of about 195,911 (265)

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

open access: yesAdvanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao   +7 more
wiley   +1 more source

Reply to Claus Juergen Preusse. [PDF]

open access: yesInterdiscip Cardiovasc Thorac Surg
Settepani F.
europepmc   +1 more source

Waning immunity and the future of booster vaccination strategies in global vaccine programs post COVID-19. [PDF]

open access: yesHum Vaccin Immunother
Biswas R   +6 more
europepmc   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission. [PDF]

open access: yesSmall
Sivakumaran N   +10 more
europepmc   +1 more source

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