Results 121 to 130 of about 812,314 (361)
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Electrical Engineering Medium Voltage Protection and Coordination [PDF]
This presentation covers the basics of the medium voltage electrical system on the Kennedy Space Center. The material will include the process of selective coordination between protective devices and the analysis of a fault that occurred in the ...
Wessner, Jason R.
core +1 more source
Estudio de la coordinación de las protecciones por métodos computarizados aplicados al centro comercial policentro [PDF]
study addresses an important field in the design of an electrical system either commercial or industrial, this is the coordination of electrical protection. The coordination of the protection depends on the good or electrical system mal function. This
Cando, Geovanny +3 more
core +1 more source
Intercompartmental communication in senescence
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Data Recovery Efforts at the Millville Mill Site (41RK223), Rusk County, Texas [PDF]
In September 1993, data recovery efforts were undertaken by Espey, Huston & Associates, Inc. (EH&A) of Austin, Texas, to mitigate the effects of lignite mining on site 41RK223 in Texas Utilities Mining Company\u27s Oak Hill/2280 Acre Mine permit area of ...
Foster, Eugene R., Jr., Glander, Wayne
core +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Comparative Law as a Bridge Between the Nation-State and the Global Economy: An Essay for Herbert Bernstein [PDF]
Professor Richard M. Buxbaum delivered the Fourth Annual Herbert L. Bernstein Memorial Lecture in Comparative Law in 2005 and this article is based on his remarks.
Buxbaum, Richard M.
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ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source

