Results 51 to 60 of about 812,314 (361)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Would global patent protection be too weak without international coordination? [PDF]

I extend the Grossman and Lai (2004) model to answer the question, "Would global patent protection be too weak without international coordination?" by introducing firmbiased government preferences and trade barriers in the model.
Edwin L.-C. Lai
core   +3 more sources

Statement of Retraction: Two transition metal coordination polymers: protection activity on renal ischemia-reperfusion injury combined with chitosan chuanqizine nanoparticles [PDF]

, 2023

openalex   +1 more source

Optimizing the roles of unit and non-unit protection methods within DC microgrids [PDF]

, 2012
The characteristic behavior of physically compact, multiterminal dc networks under electrical fault conditions can produce demanding protection requirements.
Burt, Graeme, Crolla, Paul, Fletcher, Steven, Galloway, Stuart, Norman, Patrick   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Effect of non standard characteristics of overcurrent relay on protection coordination and maximizing overcurrent protection level in distribution network

Alexandria Engineering Journal, 2022
This research employs the capabilities of 7SJ602 model (overcurrent and earth fault relay) for better performance and faster response. The Semiens 7SJ602 model is connected to the real radial system of an Egyptian Substation to protect the feeder ...
Abdallah Reda, Amal F. Abdelgawad, Mohamed Ibrahim   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A study on coupling and coordination of grain production and agricultural ecological protection in the Yangtze river economic belt [PDF]

Ciência Rural
: The Yangtze River Economic Belt is an important grain production area and ecological reserve in China. It is of great practical significance to promote coordinated development between grain production and agricultural ecological protection in this ...
Xuanzhu Meng, Linqi Liu, Yingying Cai, Xinyue Wang   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source