Results 51 to 60 of about 3,718,207 (351)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Analysis of War Optimization Algorithm in a Multi-Loop Power System Based on Directional Overcurrent Relays

Energies
In electrical power systems, ensuring a reliable, precise, and efficient relay strategy is crucial for safe and trustworthy operation, especially in multi-loop distribution systems.
Bakht Muhammad Khan, Abdul Wadood, Shahbaz Khan, Husan Ali, Tahir Khurshaid, Asim Iqbal, Ki Chai Kim   +6 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Transient and Steady-State Evaluation of Distributed Generation in Medium-Voltage Distribution Networks

Energies
As power generation systems with increasingly higher capacities are interconnected with distribution networks, a pressing need arises for a thorough analysis of their integration and the subsequent impacts on medium-voltage lines.
Daniel Guillén-López, Xavier Serrano-Guerrero, Antonio Barragán-Escandón, Jean-Michel Clairand   +3 more
doaj   +1 more source

Analysis the securable operation and protection coordination indices on multi‐objective sitting and sizing of synchronous distributed generations on distribution networks

IET Generation, Transmission & Distribution, 2023
Despite improving various technical indices such as operation and voltage profile, the integration of synchronous distributed generations (SDGs) may lead to the loss of protection coordination in the distribution network (DN). To tackle the problem, this
Hossien Shad, Majid Gandomkar, Javad Nikoukar   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Protection Coordination with Distributed Generation in Electrical System of Iraqi Distribution Grid [PDF]

Engineering and Technology Journal, 2016
The nature characteristic in conventional distribution networks is radial by single source supplying a downstream network. The interest about the environmental impacts and development in technologies have led to increase distributed generation (DG ...
Rashid H. Al-Rubayi, Ammar Abbas Majeed
doaj   +1 more source