Results 91 to 100 of about 794 (212)

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Integrating Protection Motivation Theory With Cultural Context

Journal of Cases on Information Technology
This study integrates Protection Motivation Theory (PMT) with cultural dimensions to design a cybersecurity education framework tailored to Kuwait. The study uses advanced analytical techniques like K-means clustering and Association Rule Mining (ARM) to find important patterns in how age, education level, and cultural norms (like religious adherence ...
openaire   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

The demographic and Psychological determinants of performing Mammography among the Employed Women in Medical Professions in western Iran: the Role of Threat Appraisal and Coping Appraisal

پژوهان, 2019
Background and Objective: Breast cancer is the most prevalent cause of cancer-related mortality among women. Mammography and early detection of breast cancer a play the important role in the treatment process.
Saeed Bashirian, Majid Barati, Younes Mohammadi, Leila Moaddab Shoar, Mitra Dogonchi   +4 more
doaj  

Hydrogen (H2) Recovery From Hydrogen Sulfide (H2S): Current Technologies, Challenges, and Future Outlook

Advanced Science, EarlyView.
ABSTRACT Hydrogen sulfide (H2S) can be transformed into hydrogen (H2) through several chemical and catalytic processes, offering a promising route for both waste treatment and clean H2 production. This colorless, flammable, and toxic gas is found abundantly in swamps, volcanoes, hot springs, sewages, other natural gas fields, and even in refineries and
Divyesh Cirikonda, Astrid Campos‐Mata, Sehmus Ozden, Shreyasi Chattopadhyay, Pulickel M. Ajayan   +4 more
wiley   +1 more source

The Effect of Education Based on Protection Motivation Theory on The Harmful Effects of Solar Rays on Male Students

آموزش بهداشت و ارتقاء سلامت ایران, 2015
Background and objective: Personal protection has an essential role in preventing and decreasing solar UV radiation-induced cancers. This study aimed to determine the effect of education based on protection motivation theory on the harmful effects of sun
Gholam Reza Maseudi, Esmat-Osadat Hosseini, Ramazan Mirzaei, Mahnaz Shahrakipour, Seyed Ali Hosseini   +4 more
doaj  

How People Decide to Protect Their Health: A Protection Motivation Theory–Theory of Reasoned Action Perspective

Korean Journal of Health Promotion
Background: This study investigated how perceived knowledge, threat, and coping appraisals, moral obligation, and social approval influence voluntary mask-wearing intentions within an integrated framework combining Protection Motivation Theory (PMT) and the Theory of Reasoned Action (TRA).
Changhyun NAM, Ho Yeol YU, Juyoung LEE, Elizabeth WACHIRA   +3 more
openaire   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Biomimetic Polymerization of Tellurocysteine: Breaking the Natural Amino Acid Radioprotection Limitation

Advanced Science, EarlyView.
Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen, Hanjie Zhu, Yue Zhang, Yuqing Qiao, Ruotong Deng, Huaping Xu, Wei Cao   +6 more
wiley   +1 more source