Results 51 to 60 of about 3,147,413 (303)

Intercomparisons as an important element of quality assurance in metrology of ionising radiation [PDF]

open access: yesNuclear Technology and Radiation Protection, 2015
Intercomparisons are important activities performed to ensure that the services provided by calibration laboratories to end-users follow internationally accepted standards. Ionizing radiation dosimetry intercomparisons are usually of two types -
Živanović Miloš Z.   +5 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

A Quantitatively Operational Judging Method for the Process of Large Regional Heavy Haze Event Based on Satellite Remote Sensing and Numerical Simulations

open access: yesAtmosphere, 2017
In recent years, large-area heavy haze pollution cases occur frequently in eastern China, especially evident in Beijing-Tianjin-Hebei and the surrounding regions.
Qiao Wang   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Differential patterns of ophiostomatoid fungal communities associated with three sympatric Tomicus species infesting pines in south-western China, with a description of four new species [PDF]

open access: yesMycoKeys, 2019
Bark beetles and their associated fungi, which cause forest decline and sometimes high mortality in large areas around the world, are of increasing concern in terms of forest health. Three Tomicus spp. (T. brevipilosus, T. minor and T.
Wang HuiMin   +8 more
doaj   +3 more sources

The move towards geographical indication protection within the rooibos industry : A case in point for harnessing geographical indication potential in South Africa [PDF]

open access: yes, 2008
The paper aims to reflect on the impact of harnessing GI dynamics within the South African policy environment which provides protection for GIs under trade mark law by discussing the relevance for the Rooibos industry of geographical indication (GI ...
Biénabe, Estelle   +3 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Dark Pastoral: Material Ecocriticism in the Anthropocene

open access: yesEcocene: Cappadocia Journal of Environmental Humanities, 2020
The “dark pastoral” unites the Anthropocene’s strangely sunny celebration of its fossil-fueled agriculture and technology generally with the retro-nostalgic, “pastoral” dreams of resplendent greenery, which is all too often complicit in the wealth of ...
Heather I. Sullivan
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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