Results 81 to 90 of about 3,147,413 (303)
Investor Protection and Equity Markets [PDF]
We present a simple model of an entrepreneur going public in an environment with poor legal protection of outside shareholders. The model incorporates elements of Becker's (1968) crime and punishment' framework into a corporate finance environment of ...
Andrei Shleifer, Daniel Wolfenson
core
Insights into a long life without cancer: The case of the bowhead whale
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Seeds of Transformative Change [PDF]
Steven Hartman, Serpil Oppermann
doaj +1 more source
Selection of Marine Conservation Zones
Marine Conservation Zones may contribute to the protection and recovery of the marine environment. This POSTnote examines the process and approach used to select and designate zones, and difficulties in identifying and managing suitable ...
Brown, Alastair, Wentworth, Jonathan
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ECOLOGICAL SAFETY OF THE REGIONS: ACHIEVING THE EU STANDARDS [PDF]
On the basis of comparative analysis of the results of economic, production and environ- mental activity and indexes that testify the quality of life in context of environment of European countries the main trends of maintaining the ecological safety ...
Yermoshkina, Olena
core
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Oxidation and protection of fiberglass-epoxy composite masts for photovoltaic arrays in the low Earth orbital environment [PDF]
Fiberglass-epoxy composites are considered for use as structural members for the mast of the space station solar array panel. The low Earth orbital environment in which space station is to operate is composed mainly of atomic oxygen, which has been shown
Brady, Joyce A. +3 more
core +1 more source
How New York City Used an Ecosystem Services Strategy Carried Out Through an Urban-rural Partnership to Preserve the Pristine Quality of its Drinking Water and Save Billions of Dollars [PDF]
The New York City watershed protection program may be the most well known example of economics driving a decision to invest in water based ecosystem services.
Albert F. Appleton
core

