Results 61 to 70 of about 201,885 (310)

The average accumulated effective doses (1986-2016) for the population of the settlements of the Russian Federation attributed to the zones of radioactive contamination according to the Russian Federation government resolution «on the approval of the ...

Радиационная гигиена, 2017
The Chernobyl accident in 1986 being one of the most large-scale radiation accidents in the world led to radioactive contamination of large areas in the European part of the Russian Federation and at the neighboring countries.
G. Ya. Bruk, A. B. Bazyukin, A. A. Bratilova, A. Yu. Vlasov, A. V. Gromov, T. V. Zhesko, A. N. Kaduka, M. V. Kaduka, O. S. Kravtsova, I. K. Romanovich, K. A. Saprykin, V. S. Stepanov, N. V. Titov, V. A. Yakovlev   +13 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

INTERACTION OF THE ROSTOV-ON-DON ANTI-PLAGUE INSTITUTE WITH THE OTHER INSTITUTIONS PROVIDING FOR SANITARY-EPIDEMIOLOGICAL WELFARE OF POPULATION IN REGARD TODANGEROUS INFECTIOUS DISEASES

Медицинский вестник Юга России, 2017
The Rostov-on-Don Anti-Plague Research Institute interacts with a number of health and scientific institutions of the Federal Service on Consumer Rights Protection and Human Welfare Supervision.
S. V. Titova, I. A. Shchipeleva, E. I. Markovskaya, V. D. Kruglikov, O. S. Chemisova   +4 more
doaj   +1 more source

A schematic comparison of regional human rights systems: An update

, 2006
There are three regional systems for the protection of human rights, namely: the African, the Inter-American and the European systems. This contribution provides a comparative overview of their salient features and focuses on key procedural and ...
Padilla, D., Studie- en Informatiecentrum Mensenrecht, Heyns, Ch., Human Rights in a World of Conflict and Diversity. Conceptualisation and Implementation of Human Rights (t/m 2009), Zwaak, L.F., Enforcement and supervision of the implementation of Human Rights (t/m 2009)   +5 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Promoter Methylation of HIV Coreceptor-Related Genes CCR5 and CXCR4: Original Research

Viruses
The persistence of human immunodeficiency virus (HIV) within viral reservoirs poses significant challenges to eradication efforts. Epigenetic alterations, including DNA methylation, are potential factors influencing the latency and persistence of HIV ...
Anna Esman, Svetlana Salamaikina, Alina Kirichenko, Michael Vinokurov, Darya Fomina, Kirill Sikamov, Arina Syrkina, Anastasia Pokrovskaya, Vasily Akimkin   +8 more
doaj   +1 more source

Trade liberalisation and human rights protection under the SADC [PDF]

, 2009
A dissertation submitted to the Faculty of Law University of Pretoria, in partial fulfilment of the requirements for the degree Masters of Law (LLM in Human Rights and Democratisation in Africa).

core  

Equality and Human Rights Committee: UNCRC (Incorporation) (Scotland) Bill Written Evidence [PDF]

, 2020
1.1. This Bill is a watershed moment for human rights in Scotland. It will reform the existing framework for the benefit of children living here by creating a statutory framework designed to enhance access to rights under the provisions of the UNCRC in ...
Boyle, Katie
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source