Results 71 to 80 of about 5,762,867 (344)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A disaster-resilient multi-content optical datacenter network architecture [PDF]
Cloud services based on datacenter networks are becoming very important. Optical networks are well suited to meet the demands set by the high volume of traffic between datacenters, given their high bandwidth and low-latency characteristics.
De Leenheer, Marc +4 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
This paper shows that since high penetration level of distributed generations (DGs) makes the protection coordination complicated in active electrical grids, selectivity task among relays pairs can be easily affected by on-load tap changer (OLTC) tap ...
Mohammad Sheikhi +3 more
doaj +1 more source
iPDA: An Integrity-Protecting Private Data Aggregation Scheme for Wireless Sensor Networks [PDF]
Data aggregation is an efficient mechanism widely used in wireless sensor networks (WSN) to collect statistics about data of interests. However, the shared-medium nature of communication makes the WSNs are vulnerable to eavesdropping and packet tampering/
Abdelzaher, Tarek F. +4 more
core
Encoded Recoupling and Decoupling: An Alternative to Quantum Error Correcting Codes, Applied to Trapped Ion Quantum Computation [PDF]
A recently developed theory for eliminating decoherence and design constraints in quantum computers, ``encoded recoupling and decoupling'', is shown to be fully compatible with a promising proposal for an architecture enabling scalable ion-trap quantum ...
A. Beige +64 more
core +2 more sources
Low cost, high efficiency, price transparency, and timely settlement of transactions are required for direct transactions between electricity providers and consumers in the microgrids.
Shaomin Zhang +3 more
semanticscholar +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

