Results 41 to 50 of about 2,435,517 (306)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

New concept of microprocessor protective devices design [PDF]

open access: yesSerbian Journal of Electrical Engineering, 2010
Transition from electromechanical to digital protective relays is accompanied with serious technical problems. The author offers a new approach in designing the digital relays capable of solving these problems.
Gurevich Vladimir
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Protective and positioning devices in maxillofacial prosthodontics and radiotherapy: Overview

open access: yesTechnical Innovations & Patient Support in Radiation Oncology, 2022
Background: Radiation therapy (RT) is a common modality of treatment in patients with head and neck cancer, and can cause several oral complications.
W. El Hawari, O. Bentahar
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Department of Family and Protective Services Vision

open access: yes, 2020
Newsletter of the Department of Family and Protective Services containing departmental news and announcements, deadlines, and other information of importance to Family and Protective ...
Texas. Department of Family and Protective Services.
core  

Eliciting usage contexts of safety-critical medical devices [PDF]

open access: yes, 2014
This position paper outlines our approach to improve the usage choice of suitable devices in different health care environments (contexts). Safety-critical medical devices are presumed to have undergone a thorough (user-centred) design process to ...
Reeves, Steve   +4 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

On Uffink's alternative interpretation of protective measurements [PDF]

open access: yes, 2012
Protective measurement is a new measuring method introduced by Aharonov, Anandan and Vaidman (1993). By a protective measurement, one can measure the expectation value of an observable on a single quantum system, even if the system is initially not in an
Gao, Shan, Shan Gao
core  

Face Masks Use to Avoid Airborne Contamination during COVID-19 Pandemic and Related Conditions: A Systematic Review

open access: yesIranian Journal of Public Health, 2021
Background: The facemasks use has been discussed to prevent respiratory disease due airborne contamination. The aim of this study was to perform a systematic review about the face masks use to avoid airborne contamination during COVID-19 pandemic and ...
Danúbia Cunha Sá-Caputo   +7 more
doaj   +1 more source

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