Results 181 to 190 of about 1,147,833 (267)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Understanding Risk and Protective Factors of Intimate Partner Violence: A Public Health and Social Advocacy Approach. [PDF]

Prev Sci
Natarajan M, Irvin-Erickson Y, Suh B, Nembhard S, Smith L, Lu YF.   +5 more
europepmc   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

ADHD help-seeking attitudes of Asian Americans

Frontiers in Child and Adolescent Psychiatry
Monisha Chawla, Jennalyn Vandenheuvel, Shannon L. Sibbald   +2 more
doaj   +1 more source

Risk and protective factors of near-lethal suicide attempts in adolescents. [PDF]

Front Psychiatry
Chen A, Franke S, Stolz A, Papsdorf R, von Polier G, Radeloff D.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Exploratory study of protective factors against belief in neuromyths in in-service teachers at Brazilian vocational-technical high school. [PDF]

BMC Med Educ
Teixeira DD, Oliveira MA, Sabino-Carvalho JL, de Almeida AA.   +3 more
europepmc   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Adolescents' substance use trajectories across the COVID-19 pandemic: implications of pandemic disruptions and other risk and protective factors. [PDF]

Child Dev
Serang S, Zhou W, Page L, Kelly BC, Maggs JL, Mustillo SA, Whiteman SD.   +6 more
europepmc   +1 more source