Results 61 to 70 of about 467,085 (263)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

COVID-19: emerging protective measures.

open access: yesEuropean review for medical and pharmacological sciences, 2020
The COVID-19 (Coronavirus disease 2019) spreads primarily through droplets of saliva or discharge from the nose. COVID-19 is predominantly considered as an unavoidable pandemic, and scientists are very curious about how to provide the best protection to the public before a vaccine can be made available.
Balachandar, V.   +8 more
openaire   +2 more sources

EFFICIENCY OF PROTECTIVE MEASURES TO REDUCE INTERNAL DOSE FROM CAESIUM RADIONUCLIDES FOR THE INHABITANTS OF RADIOACTIVE CONTAMINATION AREA IN THE FIRST YEARS AFTER THE CHERNOBYL ACCIDENT

open access: yesРадиационная гигиена, 2015
In the paper, we use the data on the content of caesium radionuclides in foodstuffs and in Bryansk region adult inhabitant’s body, on their food ration and its changes during the first years after the Chernobyl accident, and on the measures to protect ...
I. G. Travnikova
doaj  

Domestic violence between felony and misdemeanour law of the Republic of Srpska [PDF]

open access: yesGlasnik Advokatske komore Vojvodine, 2023
Since May 2020, a new legal solution which treats domestic violence exclusively as a felony has been in force as part of the legislature of the Republic of Srpska. In this article, the author argues against the exclusive treatment of domestic violence as
Sladić Ljubana
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

EMERGENCY BARRING ORDERS AND THE CASE-LAW OF THEIR APPLICATION

open access: yesJurisprudencija
This article analyses the new Law on Protection from Domestic Violence, which entered into force on 1 July 2023, and established emergency barring orders in Lithuania. The article discusses why there was a need for a new protection institute and analyses
Eitvydas Zurba
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Wind and Snow Protection Design and Optimization for Tunnel Portals in Central Asian Alpine Mountains

open access: yesBuildings
Aiming at the wind-blown snow disasters plaguing tunnel portals along the China-Tajikistan Highway Phase II Project, this study optimizes the protective parameters of wind deflectors through numerical simulation to improve the disaster prevention ...
Bin Zhi   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Survey of Hand Issues Encountered by Hairdressers and Hairdresser Related Professionals: From Epidemiological Data to Clinical Observational Survey Results

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Sophie Seité, Guénaëlle Le Dantec, Ann’Laure Demessant-Flavigny, Delphine Kerob Medical Department, La Roche-Posay International, Levallois-Perret, FranceCorrespondence: Delphine Kerob, Cosmétique Active International, La Roche-Posay International, 62 ...
Seité S   +3 more
doaj  

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