Results 1 to 10 of about 43,758 (65)

A new insight on copper: Promotion of collagen synthesis and myofiber growth and development in juvenile grass carp (Ctenopharyngodon idella)

open access: yesAnimal Nutrition, 2023
Copper (Cu) is a trace element, essential for fish growth. In the current study, in addition to growth performance, we first explored the effects of Cu on collagen synthesis and myofiber growth and development in juvenile grass carp (Ctenopharyngodon ...
Rui Ma   +12 more
doaj   +1 more source

Significance of Intratumoral Fibrosis in Clear Cell Renal Cell Carcinoma [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2018
Background Intratumoral fibrosis (ITF) is a frequent histologic finding in solid organ tumors. Renal cell carcinoma (RCC) is a highly vascularized tumor with different shapes and degrees of ITF and inflammation.
Jae Won Joung   +4 more
doaj   +1 more source

Histone lysine-specific demethylase 1 regulates the proliferation of hemocytes in the oyster Crassostrea gigas

open access: yesFrontiers in Immunology, 2022
BackgroundLysine-specific demethylase 1 (LSD1) is an essential epigenetic regulator of hematopoietic differentiation, which can specifically mono-methylate H3K4 (H3K4me1) and di-methylate H3K4 (H3K4me2) as a transcriptional corepressor.
Xiaoyu Gu   +19 more
doaj   +1 more source

Genetic dissection of monosaccharides contents in rice whole grain using genome‐wide association study

open access: yesThe Plant Genome, 2023
The simplest form of carbohydrates are monosaccharides which are the building blocks for the synthesis of polymers or complex carbohydrates. Monosaccharide contents of 197 rice accessions were quantified by HPAEC‐PAD in rice (Oryza sativa L.) whole grain
Rahele Panahabadi   +2 more
doaj   +1 more source

Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Articular cartilage remains among the most difficult tissues to regenerate due to its poor self-repair capacity. The lysyl oxidase family (LOX; also termed as protein-lysine 6-oxidase), mainly consists of lysyl oxidase (LO) and lysyl oxidase-like 1-4 ...
Weiping Lin   +3 more
doaj   +1 more source

The inhibition of protein-lysine 6-oxidase by various lathyrogens. Evidence for two different mechanisms [PDF]

open access: yesBiochemical Journal, 1985
Lathyrogens decrease collagen and elastin cross-linking by inhibiting lysine oxidase. The lathyrogens isoniazid and semicarbazide decrease liver pyridoxal phosphate and are teratogenic; all their effects are reversed by pyridoxal. β-Aminopropionitrile, another lathyrogen, does not affect liver pyridoxal phosphate, and its lathyrogenic and teratogenic ...
C I, Levene, M J, Carrington
openaire   +2 more sources

Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells

open access: yesBiochemistry and Biophysics Reports, 2018
Hypoxia, a hallmark characteristic of glioblastoma (GBM) induces changes in the transcriptome and the proteome of tumor cells. We discovered that hypoxic stress produces significant qualitative and quantitative changes in the protein content of secreted ...
Rajshekhar A. Kore   +6 more
doaj   +1 more source

Mural granulosa cell gene expression associated with oocyte developmental competence

open access: yesJournal of Ovarian Research, 2010
Background Ovarian follicle development is a complex process. Paracrine interactions between somatic and germ cells are critical for normal follicular development and oocyte maturation. Studies have suggested that the health and function of the granulosa
Jiang Jin-Yi   +5 more
doaj   +1 more source

Breast cancer microenvironment composition associated with high PD-L1 expression

open access: yesBMC Cancer
Background A key challenge that complicates early diagnosis, choice of treatment tactics, and prognosis of the course of breast cancer (BC) is its heterogeneity.
Vasyl Chekhun   +8 more
doaj   +1 more source

Peroxisome deficiency impacts metabolites of lysine, lipid, and polyamine metabolism in Saccharomyces cerevisiae. [PDF]

open access: yesHistochem Cell Biol
Kosir T   +6 more
europepmc   +1 more source

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