Results 101 to 110 of about 43,875 (179)

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao, Bo‐Kai Su, Ying‐Jan Wang, Ting‐Yuan Tu   +3 more
wiley   +1 more source

Collagen processing is essential for germ cell identity. [PDF]

Biol Open
Roman S, Oulhen N, Reyes G, Masina B, Wessel G.   +4 more
europepmc   +1 more source

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, Volume 13, Issue 16, 18 March 2026.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

Vafidemstat: a lysine-specific demethylase 1A inhibitor that shows promise for treating neuropsychiatric disorders. [PDF]

Epigenet Rep
Peedicayil J, Grayson DR.
europepmc   +1 more source

Mitigating drought stress and enhancing quinoa productivity using iron and zinc nanoparticles

Agrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract In recent years, the cultivation area and consumption of quinoa (Chenopodium quinoa Willd) have increased in the country due to its nutritional properties and ability to grow in adverse conditions. Based on climate change scenarios, long periods of drought are expected, which emphasizes the need for planting and developing new plants that are ...
Nasim Pakbaz, Heshmat Omidi, Mohammad Hosein Bijeh Keshavarzi   +2 more
wiley   +1 more source

Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics

Aggregate, Volume 7, Issue 3, March 2026.
Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang, Ruixuan Zheng, Jing Lin, Jiawu Weng, Lexiang Zhang, Fangfu Ye   +5 more
wiley   +1 more source

Bibliometric analysis combined with visualization on universal trends and hot topics of LOX family in human diseases: 1995 to 2025. [PDF]

Front Oncol
Yang T, Li H, Zhou W, Zhang N, Tian Z, Wang H, Feng Y, Chen Y, Wang Z.   +8 more
europepmc   +1 more source

Study on the Function and Mechanism of Neutrophil Extracellular Traps in Regulating Necroptosis Following Traumatic Brain Injury

Brain and Behavior, Volume 16, Issue 3, March 2026.
TBI induces NETs formation, as evidenced by the upregulation of PAD4 and MPO. NETs activate the necroptosis pathway via phosphorylation of RIP1‐RIP3‐MLKL, thereby exacerbating secondary brain injury (neuronal death, BBB disruption, and neuroinflammation).
Ao Li, Tian‐Wei Pei, Hao Qi, Li‐Biao Song, Juan Fang, Zhi‐Song Ding, Tao Chen   +6 more
wiley   +1 more source

A Single Flavoenzyme Forges the Pentacyclic Skeleton of α-Cyclopiazonic Acid. [PDF]

J Am Chem Soc
Wang M, Cheng T, Zhang W, Kuo YM, Li Y, Yan Y, Hisao PY, Chang CY, Wang N.   +8 more
europepmc   +1 more source

Lactate‐induced metabolic reprogramming of TAMs impairs antigen presentation capacity via C/EBPα–CD74 axis in oral squamous cell carcinoma

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
• CD74hi TAMs correlate with favourable prognosis in OSCC. • Lactate reprograms TAMs metabolism and increases mitochondrial respiration. • C/EBPα acetylation suppresses CD74 and impairs antigen presentation. • Restoring CD74 enhances T‐cell activation and limits OSCC progression.
Mengyao Wang, Mengqi Wang, Zizhen Gong, Fanrui Zeng, Zihui Ni, Rundong Zhai, Weiwen Zhu, Jiayi Zhang, Laikui Liu   +8 more
wiley   +1 more source