Results 111 to 120 of about 43,875 (179)

Role of LONP1 in human diseases: molecular mechanisms and therapeutic potential. [PDF]

Cell Mol Biol Lett
Li M, Wang A, Tang C, Qiao Y, Zhang W, Wu Y.   +5 more
europepmc   +1 more source

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Protective Functions of β-Alanyl-L-Histidine and Glycyl-L-Histidyl-L-Lysine Glycoconjugates and Copper in Concert. [PDF]

Antioxidants (Basel)
Naletova I, Rizzarelli E.
europepmc   +1 more source

Type 2 Diabetes From the Perspective of Telomere Biology

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
This graphical abstract illustrates the bidirectional relationship between the telomere/telomerase system and T2DM: telomere attrition contributes to pancreatic β‐cell dysfunction and insulin resistance through mechanisms such as oxidative stress and apoptosis, while T2DM‐related hyperglycemia and chronic inflammation further exacerbate telomere damage.
Hongye Cao, Haixia Feng, Zhen Shen, Yanqin Huang   +3 more
wiley   +1 more source

Histone methyltransferase SMYD1: playing a crucial role in disease progression. [PDF]

Front Mol Biosci
Duan L, Lou Y, Huang K, Pan K, Chen X.
europepmc   +1 more source

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, Volume 7, Issue 2, March 2026.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Gastrectomy promoted diabetes remission involves the molecular clock and epigenetic mechanisms in a rat model of lean type 2 diabetes. [PDF]

Sci Rep
Le Lay A, Brial F, Rouch C, Shao X, Bourgey M, Sonomura K, Ou H, Ghezzal S, Vincent M, Rugard M, Audouze K, Ragoussis J, Matsuda F, Bourque G, Grundberg E, Lathrop M, Magnan C, Gauguier D.   +17 more
europepmc   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Processes and therapeutic perspectives of acylation modifications of lysine and cysteine in tumors. [PDF]

Cell Commun Signal
Jiang J, Chen J, Huang S, Tian Y, Liu L, Yao J, Zhang Y, Jiang C, Zhang X, Han N, Shu G, Yin G, Yip LX, Xing K, Leong DT, Wang M.   +15 more
europepmc   +1 more source

A Comprehensive Review on the Significance of Antioxidants and Their Influence on Biopolymer Packaging Films: Recent Advances and Challenges

Food Frontiers, Volume 7, Issue 2, March 2026.
Influence of antioxidants‐loaded biopolymer films on food security and extended shelf life. ABSTRACT Autooxidation is a significant cause of quality deterioration in food systems, leading to nutrient loss, off‐flavor formation, textural changes, and overall spoilage.
Sai Kumar Tammina, Rambabu Krishnamoorthy, Arshied Manzoor, Ruchir Priyadarshi, Kandi Sridhar, Fawzi Banat   +5 more
wiley   +1 more source