RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Role of novel protein acylation modifications in sepsis. [PDF]
Wang J +6 more
europepmc +1 more source
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Phylogenomic reclassification of Cellulophaga species to Paracellulophaga gen. nov. and description of Allocellulophaga tsushimaensis gen. nov., sp. nov., a novel bacterium from coastal seawater of Tsushima Island, Japan. [PDF]
Nakajima Y +11 more
europepmc +1 more source
The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance
One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang +3 more
wiley +1 more source
Ten novel psychrophilic <i>Flavobacterium</i> species from Tibetan Plateau glaciers define a cryospheric lineage with global cold-origin relatives. [PDF]
Liu Q, Yang LL, Xin YH.
europepmc +1 more source
ABSTRACT The ubiquitin‐dependent Arg/N‐degron pathway relates the stability of a substrate protein to the nature of its N‐terminal amino acid residue or its biochemical modifications, with some N‐terminal residues being recognized by specific E3 ubiquitin ligases, resulting in the ubiquitylation and degradation of the substrate protein.
Brian C. Mooney +3 more
wiley +1 more source
Tannic Acid Achieves Rapid Scar-Free Corneal Healing by Chelating Excess Copper to Suppress Aberrant LOX-Mediated Fibrosis. [PDF]
Cai M +6 more
europepmc +1 more source
Iron deficiency anaemia remains a major public health challenge in Sub‐Saharan Africa, where population growth, displacement and limited resources heighten nutritional insecurity. We compiled a list of indigenous African underutilized wild food plants and examined their potential for addressing micronutrient deficiencies.
Eltayb Abdellatef +2 more
wiley +1 more source
The function and mechanisms of action of lysyl oxidase-like 3 (LOXL3) in cancers. [PDF]
Zhao D +9 more
europepmc +1 more source

