Results 141 to 150 of about 43,875 (179)

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

Phytotherapy Research, Volume 40, Issue 3, Page 965-985, March 2026.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao, Tao Xu, Chao Ye, Ke Zhang, Xinyu Heng, Shaohong Huang, Yan Chen, Yitong Guo, Shengyi Shao, Zhi Wen, Chenwen Shao, Xiang Lu, Ning Sun, Hai Yang   +13 more
wiley   +1 more source

Combining computer-aided enzyme design and chromosomal integration for plasmid-free biosynthesis of 1,5-pentanediol in Escherichia coli. [PDF]

Microb Cell Fact
Deng H, Wang J, Meng F, Ma C, Li J, Wang J, Wang X, Zhao C, Zhang Y, Wang R, Chen N.   +10 more
europepmc   +1 more source

Review of Amino Acid Foliar Application as a Stress Mitigation Strategy: Unraveling the Protective Mechanisms Against Abiotic Stress

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 1, March 2026.
ABSTRACT The foliar application of amino acids offers a promising strategy to mitigate multiple abiotic stresses—drought, salinity, heat and heavy metals—by enhancing plant physiological, biochemical and molecular responses. This review synthesises recent advances in understanding how external amino acids function as bio‐stimulants, focusing on ...
Xiaoyu Ma, Mirezhatijiang Kayoumu, Yue Yin, Zewen Wang, Guilan Duan   +4 more
wiley   +1 more source

Mechanisms of Protection Against Oxidative Stress During Hibernation. [PDF]

Int J Mol Sci
Shemarova IV, Nikitina ER.
europepmc   +1 more source

Linking Nutritional, Sensory, and Functional Quality in Plant‐Based Proteins Through Structural Modification and Computational Insights

Sustainable Food Proteins, Volume 4, Issue 1, March 2026.
The lacking essential amino acids, low digestibility, bioavailability, bitterness, and presence of anti‐nutritional factors that limit the consumption of plant proteins and their use in food formulations are discussed comprehensively. The findings of recent studies on novel technologies and computer‐based applications used to cope with these challenges
Humeyra Cavdar Dincturk, Rukiye Gundogan, Asli Can Karaca, Esra Capanoglu   +3 more
wiley   +1 more source

Effects of glucose oxidase combined with clostridium butyricum on broiler growth performance, nutrient digestibility, antioxidant function, intestinal barrier, and intestinal microbiota. [PDF]

Poult Sci
Guo Y, Zheng T, Wang M, Chen D, Huang Z, Liu G, Zhong L, Li Y, Jiang Z, Du H, Zhang C.   +10 more
europepmc   +1 more source

Mechanistic Insights Into the Biosynthesis of Pseurotin A in Aspergillus fumigatus

Small Structures, Volume 7, Issue 3, March 2026.
This study reveals the cryo‐EM structure of the PsoA, a key hybrid PKS‐NRPS enzyme in fungal secondary metabolism. The findings uncover a dimeric architecture and the specific PsoA–PsoF interaction and identify a dynamic loop in the KS domain that acts as a checkpoint for polyketide chain length and methylation timing, providing fundamental molecular ...
Lei Sun, Zi‐Long You, Rui‐Qing Lyu, Zhao‐Bin Wang, Ming Ma, Lin Bai   +5 more
wiley   +1 more source

Hypoxic Reprogramming of ACOX1-Driven HSP90AB1 Crotonylation Stabilizes Thioredoxin to Orchestrate Redox Homeostasis in Oral Squamous Cell Carcinoma. [PDF]

Research (Wash D C)
Yin X, Zhang Y, Zhang Y, Zhou M, Zhang J, Wang Z, Xu W, Song C, Ran J, Lin L, Luo X, Han W.   +11 more
europepmc   +1 more source

Current insights into long non-coding RNAs role for insulin resistance emerging in type 2 diabetes mellitus and its complications. [PDF]

Toxicol Rep
Abdel-Megeed RM.
europepmc   +1 more source