Results 211 to 220 of about 184,784 (335)

CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn.

, 1992
Karl Burgess, Masahiro Yamamoto, Kartik Prasad, Christopher E. Rudd   +3 more
openalex   +1 more source

Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon [PDF]

, 1993
Chinthalapally V. Rao, Barbara Simi, Bandaru S. Reddy   +2 more
openalex   +1 more source

TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah, Daniel A. Arber, Devendra K. Hiwase   +2 more
wiley   +1 more source

Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex.

, 1994
Che‐Leung Law, Sidorenko Sp, K A Chandran, Kay Draves, Andrew C. Chan, Arthur Weiss, Susanne Edelhoff, Christine M. Distèche, Edward A. Clark   +8 more
openalex   +1 more source

A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators. [PDF]

, 1991
Yaacov Ben‐David, K Letwin, Lisa R. Tannock, Alan Bernstein, Tony Pawson   +4 more
openalex   +1 more source

Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives

American Journal of Hematology, EarlyView.
ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley   +1 more source

Clonal Hematopoiesis and Thrombosis

American Journal of Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
wiley   +1 more source

Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore, Gianmichele Migaleddu, Pei‐Chien Tsai, Antonella Fogli, Maria Adelaide Caligo, Gabriele Siciliano, Mirco Cosottini, Yi‐Chung Lee, Yi‐Chu Liao, Michelangelo Mancuso, Roberto Ceravolo, Daniela Frosini   +11 more
wiley   +1 more source

Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement.

, 1994
Anne L. Burkhardt, Becky A. Stealey, R. Rowley, S Mahajan, Margaret Prendergast, Joseph Fargnoli, Joseph B. Bolen   +6 more
openalex   +1 more source

Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase. [PDF]

, 1993
Jianguo Wu, Jeffrey K. Harrison, L A Vincent, Clare M.M. Haystead, Timothy Haystead, H Michel, Donald F. Hunt, Kevin R. Lynch, T W Sturgill   +8 more
openalex   +1 more source