Results 211 to 220 of about 817,279 (353)
Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6
Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee+3 more
wiley +1 more source
The Role of Tyrosine Kinase in Beauty and Skincare: A Comprehensive Review. [PDF]
Li Z.
europepmc +1 more source
Differential inhibition of T cell receptor signal transduction and early activation events by a selective inhibitor of protein-tyrosine kinase. [PDF]
James M. Trevillyan+4 more
openalex +1 more source
Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu+12 more
wiley +1 more source
Matrix metalloproteinases and protein tyrosine kinases: potential novel targets in acute lung injury and ARDS. [PDF]
Aschner Y+3 more
europepmc +1 more source
The Fps/Fes protein-tyrosine kinase promotes angiogenesis in transgenic mice. [PDF]
Peter A. Greer+5 more
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source