Results 41 to 50 of about 843,752 (300)

Dynamics of Co-translational Membrane Protein Integration and Translocation via the Sec Translocon [PDF]

, 2020
An important aspect of cellular function is the correct targeting and delivery of newly synthesized proteins. Central to this task is the machinery of the Sec translocon, a transmembrane channel that is involved in both the translocation of nascent ...
Miller, Thomas F., III, Niesen, Michiel J. M., Zimmerman, Michael H.   +2 more
core  

Molecular analysis of the early interaction between the grapevine flower and Botrytis cinerea reveals that prompt activation of specific host pathways leads to fungus quiescence [PDF]

, 2017
Grape quality and yield can be impaired by bunch rot, caused by the necrotrophic fungus Botrytis cinerea. Infection often occurs at flowering, and the pathogen stays quiescent until fruit maturity.
Agudelo-Romero, Alkan, Amselem, Asselbergh, Bhuiyan, Birkenbihl, Blanco-Ulate, Boller, Bradley, Brutus, Caffall, Cantu, Choquer, Coertze, Conesa, Costa, Dadakova, Dalmais, De Cremer, Deytieux-Belleau, Du, Eichorn, Elmer, Espino, Favaron, Giannakis, Gilbert, Godfrey, Goetz, Grimplet, Guetsky, Hammerbacher, Hellemans, Höll, Jaillon, Jarvis, Jarvis, Jeandet, Jersch, Kan, Kan, Kan, Keller, Kelloniemi, Kemmerling, Kretschmer, Langcake, Law, Lebel, Lee, Leroch, Leroch, Liao, Liao, Lijavetzky, Liu, Malacarne, Marrs, Martin, McClellan, McNicol, Merz, Mlikota-Gabler, Mohnen, Monteiro, Moretto, Mullins, Nagpala, Nair, Naoumkina, Noda, Padgett, Pezet, Pezet, Prusky, Prusky, Prusky, Puhl, Rieu, Rolke, Rossi, Ruijter, Schouten, Schouten, Schumacher, Schumacher, Shaw, Smith, Smyth, Thimm, Vandesompele, Vannozzi, Velasco, Volodarsky, Vrhovsek, Waite, Weng, Wiermer, Williamson, Williamson, Zhang, Zhang, Zhao   +102 more
core   +1 more source

Iron-sulphur protein catalysed [4+2] cycloadditions in natural product biosynthesis

Nature Communications
To the best of our knowledge, enzymes that catalyse intramolecular Diels-Alder ([4+2] cycloaddition) reactions are frequently reported in natural product biosynthesis; however, no native enzymes utilising Lewis acid catalysis have been reported ...
Yu Zheng, Katsuyuki Sakai, Kohei Watanabe, Hiroshi Takagi, Yumi Sato-Shiozaki, Yuko Misumi, Yohei Miyanoiri, Genji Kurisu, Toshihiko Nogawa, Ryo Takita, Shunji Takahashi   +10 more
doaj   +1 more source

The Potential of Narrative for Understanding Protein Biosynthesis in the Context of Viral Infections

Education Sciences
Based on the assumption that the process of understanding is partly narrative, this study explores the potential benefits and limitations of using narrative writing in biology education.
Jörg Zabel, Cornelia Averdunk
doaj   +1 more source

Interference of Arabidopsis N-Acetylglucosamine-1-P Uridylyltransferase Expression Impairs Protein N-Glycosylation and Induces ABA-Mediated Salt Sensitivity During Seed Germination and Early Seedling Development

Frontiers in Plant Science, 2022
N-acetylglucosamine (GlcNAc) is the fundamental amino sugar moiety that is essential for protein glycosylation. UDP-GlcNAc, an active form of GlcNAc, is synthesized through the hexosamine biosynthetic pathway (HBP).
Ya-Huei Chen, Ya-Huei Chen, Hwei-Ling Shen, Shu-Jen Chou, Yasushi Sato, Wan-Hsing Cheng, Wan-Hsing Cheng   +6 more
doaj   +1 more source

Dissecting a complex chemical stress: chemogenomic profiling of plant hydrolysates. [PDF]

, 2013
The efficient production of biofuels from cellulosic feedstocks will require the efficient fermentation of the sugars in hydrolyzed plant material.
Arkin, Adam P, Bauer, Stefan, Baumohl, Jason K, Deutschbauer, Adam M, Hazen, Terry, Hu, Ping, Ibáñez, Ana B, Leon, Dacia, Mar, Jordan S, Mitchell, Valerie D, Price, Morgan N, Skerker, Jeffrey M, Tarjan, Daniel R, Wetmore, Kelly M, Wu, Cindy H   +14 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Incomplete Wood-Ljungdahl pathway facilitates one-carbon metabolism in organohalide-respiring Dehalococcoides mccartyi. [PDF]

, 2014
The acetyl-CoA "Wood-Ljungdahl" pathway couples the folate-mediated one-carbon (C1) metabolism to either CO2 reduction or acetate oxidation via acetyl-CoA.
Alvarez-Cohen, Lisa, Bill, Markus, Brisson, Vanessa L, Conrad, Mark E, Feng, Xueyang, Men, Yujie, Tang, Yinjie J, Yi, Shan, Zhuang, Wei-Qin   +8 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Mechanistic Insights into Clinically Relevant Ribosome-Targeting Antibiotics

Biomolecules
Antibiotics targeting the bacterial ribosome are essential to combating bacterial infections. These antibiotics bind to various sites on the ribosome, inhibiting different stages of protein synthesis.
Szymon J. Krawczyk, Marta Leśniczak-Staszak, Ewelina Gowin, Witold Szaflarski   +3 more
doaj   +1 more source