A Second Gene for Acyl-(Acyl-Carrier-Protein): Glycerol-3-Phosphate Acyltransferase in Squash, Cucurbita moschata cv. Shirogikuza*, Codes for an Oleate-Selective Isozyme: Molecular Cloning and Protein Purification Studies [PDF]
Ikuo Nishida+3 more
openalex +1 more source
Two Sugarcane Expansin Protein-Coding Genes Contribute to Stomatal Aperture Associated with Structural Resistance to Sugarcane Smut. [PDF]
Liu Z, Yu Z, Li X, Cheng Q, Li R.
europepmc +1 more source
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
Integrative multi-omics analysis identifies novel protein-coding genes and pathways in autism spectrum disorder: a comprehensive study. [PDF]
Liu D, Liu Y, Fang X.
europepmc +1 more source
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang+8 more
wiley +1 more source
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran+5 more
wiley +1 more source
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu+6 more
wiley +1 more source
Transcriptomic Profiles of Long Noncoding RNAs and Their Target Protein-Coding Genes Reveals Speciation Adaptation on the Qinghai-Xizang (Tibet) Plateau in Orinus. [PDF]
Min Q+11 more
europepmc +1 more source
A Vertically‐Stacked Optoelectronic Sensor for Localized Hemodynamics Monitoring
This work introduces a hemodynamics monitoring sensor that features vertically stacked microLEDs and a heterogeneously integrated photodetector. The vertically stacked microLEDs enable localized measurements, and by designing the interoptode distance according to the depth of the target region, this vertically stacked optoelectronic sensor is ...
Taeyeon Lee+9 more
wiley +1 more source