Results 11 to 20 of about 7,315 (215)

The human protein disulfide isomerase gene family [PDF]

Human Genomics, 2012
Enzyme-mediated disulfide bond formation is a highly conserved process affecting over one-third of all eukaryotic proteins. The enzymes primarily responsible for facilitating thiol-disulfide exchange are members of an expanding family of proteins known ...
Galligan James J, Petersen Dennis R
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Atypical protein disulfide isomerases (PDI): Comparison of the molecular and catalytic properties of poplar PDI-A and PDI-M with PDI-L1A. [PDF]

PLoS ONE, 2017
Protein disulfide isomerases are overwhelmingly multi-modular redox catalysts able to perform the formation, reduction or isomerisation of disulfide bonds. We present here the biochemical characterization of three different poplar PDI isoforms.
Benjamin Selles, Flavien Zannini, Jérémy Couturier, Jean-Pierre Jacquot, Nicolas Rouhier   +4 more
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Thiol isomerase ERp18 enhances platelet activation and arterial thrombosis [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Thiol isomerases regulate the thiol-disulfide exchange of functional proteins in cells. Using genetically modified mouse models and inhibitors, we and others demonstrated that 7 thiol isomerases (ERp57, protein diisulfide isomerase, ERp72 ...
Chao He, Aizhen Yang, Keyu Lv, Yuxin Zhang, Zhenzhen Zhao, Yi Lu, Chao Fang, Yue Han, Depei Wu, Miao Jiang, Jingyu Zhang, Yi Wu   +11 more
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Structural, functional and proteomic changes of proteins during rice yellowing [PDF]

Food Chemistry: X
High temperature storage (40 °C, 60 % relative humidity, 6 months) induces rice yellowing and affects protein properties. Physiochemical analysis revealed increased disulfide bonds, particle size, and surface hydrophobicity in yellowed rice protein ...
Yuqian Liu, Yanan Qv, Jingyu Sun, Xiao Zheng, Victoria Anthony Uyanga, Yawen Wang, Yu Cui, Caiyun Tang, Jinguang Liu, Yilun Chen   +9 more
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Protein disulfide isomerase A6 (PDIA6) is essential for acrosome biogenesis and male fertility in mice [PDF]

Cell Communication and Signaling
Background The family of protein disulfide isomerases (PDIs) are thiol oxidoreductases located predominantly in the endoplasmic reticulum that catalyze thiol-disulfide exchange for normal protein folding.
Xiaofeng Yan, Yaqiong Zhang, Aizhen Yang, Yufeng Hou, Raymond B. Birge, Jinxing Lv, Yi Wu   +6 more
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Decoding PDI diversity: Insights into structure, domains, and functionality in sorghum [PDF]

Computational and Structural Biotechnology Journal
Proteins play indispensable roles in cellular function, acting as both structural components and catalysts for essential biological processes. Their proper folding into three-dimensional structures is critical for functionality. To ensure correct folding,
Carla F. López-Gómez, Marc T. Morris, Karen Massel, Millicent Smith, Peter Crisp, Gerhard Schenk, Ian D. Godwin   +6 more
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Atypical thioredoxin Patrx2 enhances alginate production in mucoid Pseudomonas aeruginosa [PDF]

Redox Biology
Pseudomonas aeruginosa, an opportunistic human pathogen, is known for its ability to respond and adapt to its environment, employing intricate adaptation mechanisms that can lead to the formation of complex biofilms.
Marie M. Grandjean, James N. Sturgis, Edwige B. Garcin, Moly Ba, Olivier Bornet, Christophe Bordi, Latifa Elantak, Corinne Sebban-Kreuzer   +7 more
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The leader of the capsid protein from Feline calicivirus must be palmitoylated and form oligomers through disulfide bonds for efficient viral replication [PDF]

Journal of Virology
Feline calicivirus (FCV), a member of the genus Vesivirus and a model for studying members of the family Caliciviridae, has been used to understand the biology and viral replication of etiological agents of medical and veterinary importance.
Yoatzin Peñaflor-Téllez, Jaury Gómez de la Madrid, Erick Ignacio Monge-Celestino, Carolina Pérez-Ibáñez, Randy Seir Llanas Vázquez, Sharon Itzel Sosa Mondragon, Carlos Emilio Miguel-Rodríguez, Ana Lorena Gutiérrez-Escolano   +7 more
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Downregulated miR-181a alleviates H2O2-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts [PDF]

Anais Brasileiros de Dermatologia, 2023
Background Oxidative stress is strongly associated with cellular senescence. Numerous studies have indicated that microRNAs (miRNAs) play a critical part in cellular senescence.
Yan Huang, Huimin Yan, Yanqing Yang, Jinfei Zhou, Qijun Xu, Hu Meng   +5 more
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Comparative Genome Analyses of Plant Rust Pathogen Genomes Reveal a Confluence of Pathogenicity Factors to Quell Host Plant Defense Responses

Plants, 2022
Switchgrass rust caused by Puccinia novopanici (P. novopanici) has the ability to significantly affect the biomass yield of switchgrass, an important biofuel crop in the United States. A comparative genome analysis of P.
Raja Sekhar Nandety, Upinder S. Gill, Nick Krom, Xinbin Dai, Yibo Dong, Patrick X. Zhao, Kirankumar S. Mysore   +6 more
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