Results 311 to 320 of about 543,220 (340)

Mapping Protein–DNA Interactions Using ChIP-Sequencing

2011
Chromatin immunoprecipitation (ChIP) allows enrichment of genomic regions which are associated with specific transcription factors, histone modifications, and indeed any other epitopes which are present on chromatin. The original ChIP methods used site-specific PCR and Southern blotting to confirm which regions of the genome were enriched, on a ...
Massie, Charles E, Mills, Ian G
openaire   +3 more sources

Mapping RNA–Protein Interactions Using Iodine Footprinting

Cold Spring Harbor Protocols, 2014
Footprinting methods are used to determine the binding site of a protein on an RNA. They are based on the fact that a protein bound to an RNA protects the RNA from cleavage by chemicals or nucleases. The footprinting method described here relies on the ability of iodoethanol to cleave the backbone of RNA when a phosphodiester bond contains sulfur in ...
openaire   +2 more sources

Construction and Prediction of Protein-Protein Interaction Maps

2002
With the completion of full genome sequence for several model organisms, new approaches are emerging to comprehensively characterize the function of gene products. In these so-called functional proteomics approaches, large-scale assays on the complete set of proteins of a given organism — the proteome — enable the study of the function of proteins in ...
openaire   +2 more sources

Mapping protein-protein interactions with alkaline phosphatase fusion proteins

2001
Publisher Summary This chapter describes a convenient and versatile method for determining the molecular recognition properties of SH3 domains, using bacterial alkaline phosphatase as a fusion protein. A variety of proteins or peptides have been fused to the N terminus of alkaline phosphatase (AP) by genetic engineering, including antibody chains and
M, Yamabhai, B K, Kay
openaire   +2 more sources

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Highly accurate protein structure prediction with AlphaFold

Nature, 2021
John M Jumper, Richard Evans, Alexander Pritzel   +2 more
exaly  

The protein corona from nanomedicine to environmental science

Nature Reviews Materials, 2023
Assist Prof Morteza Mahmoudi, Markita P Landry, Roxana Coreas   +2 more
exaly  

Protein-protein interaction mapping of phospholipase

2023
Ananya Samanta, Semanti Ghosh, Angshuman Bagchi   +2 more
openaire   +1 more source

Treatment of renal cell carcinoma: Current status and future directions

Ca-A Cancer Journal for Clinicians, 2017
Pedro Coelho Barata, Brian I Rini
exaly  

Current recommendations and recent progress in endometrial cancer

Ca-A Cancer Journal for Clinicians, 2019
Gini F Fleming
exaly