Results 231 to 240 of about 564,359 (343)

Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik, Benjamin Barthel, Nanna R. Andersen, Sofie V. Skriver, Alan J. Russell, John Vissing   +5 more
wiley   +1 more source

Positive cooperativity in guanosine 3':5'-monophosphate binding to guanosine 3':5'-monophosphate-dependent protein kinase.

, 1979
R. W. McCUNE, Gordon N. Gill
openalex   +1 more source

Hormonally specific expression of cardiac protein kinase activity [PDF]

, 1979
J S Hayes, Laurence L. Brunton, Joan Heller Brown, James B. Reese, Steven E. Mayer   +4 more
openalex   +1 more source

A comprehensive exploration of the druggable conformational space of protein kinases using AI-predicted structures. [PDF]

PLoS Comput Biol
Herrington NB, Li YC, Stein D, Pandey G, Schlessinger A.   +4 more
europepmc   +1 more source

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source

Cyclic Adenosine 3′:5′-Monophosphate-dependent Protein Kinase

, 1973
Francis A. Neelon, Bruce M. Birch
openalex   +1 more source

A revised nomenclature for the lemur family of protein kinases. [PDF]

Commun Biol
Mórotz GM, Bradbury NA, Caluseriu O, Hisanaga SI, Miller CCJ, Swiatecka-Urban A, Lenz HJ, Moss SJ, Giamas G.   +8 more
europepmc   +1 more source

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

Arthritis Care &Research, EarlyView.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner, Anna Shmagel, Gerd Horneff, Ivan Foeldvari, Jordi Antón, Athimalaipet V. Ramanan, Yuli Qian, Kristina Unnebrink, Shuai Hao, Heidi S. Camp, Nasser Khan, Wei Liu, Mohamed‐Eslam F. Mohamed   +12 more
wiley   +1 more source

Regulation of protein synthesis: Activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2 [PDF]

, 1978
Daniel H. Levin, Irving M. London
openalex   +1 more source

Navigating the Maze of Kinases: CaMK-like Family Protein Kinases and Their Role in Atherosclerosis. [PDF]

Int J Mol Sci
Teuwen JTJ, van der Vorst EPC, Maas SL.
europepmc   +1 more source