Results 231 to 240 of about 875,741 (363)

Dietary Fat and Fiber Alter Rat Colonic Protein Kinase C Isozyme Expression

, 1995
Laurie A. Davidson, Joanne R. Lupton, Yi-Hai Jiang, Wen‐Chi Chang, Harold M. Aukema, Robert S. Chapkin   +5 more
openalex   +1 more source

Additional file 3 of Quantitative Structure–Mutation–Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction

, 2020
Liang‐Chin Huang, Wayland Yeung, Ye Wang, Huimin Cheng, Aarya Venkat, Sheng Li, Ping Ma, Khaled Rasheed, Natarajan Kannan   +8 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

The Effect of Caffeine on Wnt/β-Catenine and P38 Mitogen-Activated Protein Kinases (MAPK) Signal Pathways and Some Biochemical Parameters on Cafeteria Diet in Rats. [PDF]

Food Sci Nutr
Baser L, Atakisi E.
europepmc   +1 more source

Regulation of bradykinin-induced Ins(1,4,5)P3 formation by protein kinase C in human fibroblasts

, 1996
Hsueh‐Meei Huang, Gary Gibson
openalex   +1 more source

Additional file 7 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

, 2020
Hui Liu, Wei Qü, Kaikai Zhu, Zong‐Ming Cheng   +3 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Probenecid Inhibits NLRP3 Inflammasome Activity and Mitogen-Activated Protein Kinases (MAPKs). [PDF]

Biomolecules
Jones LP, Martin DE, Murray J, Sancilio F, Tripp RA.   +4 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Saffron and <i>Calculus bovis</i> combination exerts anti-hepatic fibrotic effect in liver fibrosis rats <i>via</i> the mitogen-activated protein kinases pathway. [PDF]

World J Gastroenterol
Sun SN, Wang K, Xu Y, Ye F, Xia WN, Wang ZW, Liu F, He ZX, Chen M, Du QH.   +9 more
europepmc   +1 more source