FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Identifying and evaluating understudied protein kinases using biological and chemical criteria. [PDF]
RSC Med ChemKoch S, Bajorath J.
europepmc +1 more source
Involvement of Protein Kinase A in Nitric Oxide Stimulating Effect on a BKCa Channel of Human Dermal Fibroblasts [PDF]
, 2007 Si Young Roh, Seyong Choi, Inja Lim
openalex +1 more source
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
Pharmacological Reviews, 2010 S. Francis, J. Busch, J. Corbin
semanticscholar +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Classification of Calcium-Dependent Protein Kinases and Their Transcriptional Response to Abiotic Stresses in Halophyte <i>Nitraria sibirica</i>. [PDF]
Plants (Basel)Lu L +6 more
europepmc +1 more source
Redox regulation of protein kinases
Critical reviews in biochemistry and molecular biology, 2013 Thu H. Truong, Kate S. Carroll
semanticscholar +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Targeting JNK1/2 and P38 Mitogen-Activated Protein Kinases With Pazopanib Mitigates Bleomycin-Induced Lung Fibrosis. [PDF]
Arch Pharm (Weinheim)Abdelhady R +8 more
europepmc +1 more source