Results 271 to 280 of about 6,819,213 (411)

Involvement of Ca2+/calmodulin-dependent protein kinase II in the activation of carnitine palmitoyltransferase I by okadaic acid in rat hepatocytes [PDF]

, 1997
Guillermo Velasco, Manuel Guzmán, Victor A. Zammit, Math J.H. Geelen   +3 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Exploring the conformational landscape of protein kinases. [PDF]

Curr Opin Struct Biol
Gough NR, Kalodimos CG.
europepmc   +1 more source

Protein kinases: evolution of dynamic regulatory proteins.

TIBS -Trends in Biochemical Sciences. Regular ed, 2011
Susan S. Taylor, A. Kornev
semanticscholar   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The Effect of Caffeine on Wnt/β-Catenine and P38 Mitogen-Activated Protein Kinases (MAPK) Signal Pathways and Some Biochemical Parameters on Cafeteria Diet in Rats. [PDF]

Food Sci Nutr
Baser L, Atakisi E.
europepmc   +1 more source

Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans [PDF]

, 2018
Stefan Lutz, Mathias Falcenberg, Fausto Machicao, Andreas Peter, Martin Kächele, Elko Randrianarisoa, Angela Lehn‐Stefan, Róbert Wágner, Jürgen Machann, Fritz Schick, Martin Heni, Axel Ullrich, Andreas Fritsche, Norbert Stefan, Hans‐Ulrich Häring, Harald Staiger, Kοnstantinos Kantartzis   +16 more
openalex   +1 more source

Active and Inactive Protein Kinases: Structural Basis for Regulation

Cell, 1996
L. Johnson, M. Noble, D. Owen
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Unraveling Cancer’s Wnt Signaling: Dynamic Control through Protein Kinase Regulation

Deniz Tümen, Philipp Heumann, Julia Huber, Nele Hahn, Celina Macek, Martha Ernst, Arne Kandulski, C Kunst, Karsten Gülow   +8 more
openalex   +1 more source