Results 301 to 310 of about 6,714,405 (407)

A comprehensive exploration of the druggable conformational space of protein kinases using AI-predicted structures. [PDF]

PLoS Comput Biol
Herrington NB, Li YC, Stein D, Pandey G, Schlessinger A.   +4 more
europepmc   +1 more source

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases.

Journal of Biological Chemistry, 1991
Peter J. Kennelly, E. Krebs
semanticscholar   +1 more source

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

Calcium-dependent protein kinases 5 and 13 enhance salt tolerance in rice by directly activating OsMPK3/6 kinases. [PDF]

Plant Physiol
Su S, Jiang Y, Zhu X, Yu S, Wang F, Xue L, Cui H.   +6 more
europepmc   +1 more source

Interaction of the Subunits of Adenosine 3′:5′-Cyclic Monophosphate-Dependent Protein Kinase of Muscle

, 1971
Charles O. Brostrom, Jackie D. Corbin, Carol A. King, E G Krebs   +3 more
openalex   +1 more source

Regulation of splicing by SR proteins and SR protein-specific kinases

Chromosoma, 2013
Zhihong Zhou, Xiang-Dong Fu
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Navigating the Maze of Kinases: CaMK-like Family Protein Kinases and Their Role in Atherosclerosis. [PDF]

Int J Mol Sci
Teuwen JTJ, van der Vorst EPC, Maas SL.
europepmc   +1 more source

Light-stimulated phosphorylation of rhodopsin in the retina: the presence of a protein kinase that is specific for photobleached rhodopsin.

, 1975
Michael Weller, N. Virmaux, P. Mandel
openalex   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source