Results 311 to 320 of about 845,655 (386)

Author Correction: Protein kinases: drug targets for immunological disorders. [PDF]

Nat Rev Immunol
Castelo-Soccio L, Kim H, Gadina M, Schwartzberg PL, Laurence A, O'Shea JJ.   +5 more
europepmc   +1 more source

Bioprinted Micro‐Clots for Kinetic Analysis of Endothelial Cell‐Mediated Fibrinolysis

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper describes the development of a microscale model that quantifies the breakdown of fibrin by endothelial cells. The small size scale of this engineered system enables fibrin breakdown to be observed without the addition of external activators. This system could help in identifying compounds which both promote and hinder thrombosis.
Jonathan J. Chang, Kelsey Brew, Jamie A.G. Hamilton, Varun Kumar, José A. Diaz, Shuichi Takayama   +5 more
wiley   +1 more source

Comparative studies on cyclic AMP binding and protein kinase in cyclic AMP-responsive and -unresponsive Walker 256 mammary carcinomas.

, 1977
Yoon S. Cho‐Chung, Timothy Clair, Ping Yi, Clifford Parkison   +3 more
openalex   +1 more source

Identification of mitogen-activated protein kinases substrates in Arabidopsis using kinase client assay. [PDF]

Plant Signal Behav
Bahk S, Ahsan N, An J, Kim SH, Ramadany Z, Hong JC, Thelen JJ, Chung WS.   +7 more
europepmc   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

Depressed cardiac cyclic GMP-dependent protein kinase in spontaneously hypertensive rats and its further depression by guanethidine

, 1976
J.F. Kuo, Craig W. Davis, James Tse
openalex   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Aripiprazole, but Not Olanzapine, Alters the Response to Oxidative Stress in Fao Cells by Reducing the Activation of Mitogen-Activated Protein Kinases (MAPKs) and Promoting Cell Survival. [PDF]

Int J Mol Sci
Kramar B, Pirc Marolt T, Yilmaz Goler AM, Šuput D, Milisav I, Monsalve M.   +5 more
europepmc   +1 more source