Results 351 to 360 of about 845,655 (386)
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DNA Repair, 2004
Checkpoint kinase 2 (Chk2) is a multifunctional enzyme whose functions are central to the induction of cell cycle arrest and apoptosis by DNA damage. Insight into Chk2 has derived from multiple approaches. Biochemical studies have addressed Chk2 structure, domain organization and regulation by phosphorylation.
Jinwoo Ahn, Marshall Urist, Carol Prives
openaire +2 more sources
Checkpoint kinase 2 (Chk2) is a multifunctional enzyme whose functions are central to the induction of cell cycle arrest and apoptosis by DNA damage. Insight into Chk2 has derived from multiple approaches. Biochemical studies have addressed Chk2 structure, domain organization and regulation by phosphorylation.
Jinwoo Ahn, Marshall Urist, Carol Prives
openaire +2 more sources
2021
Bacteria are able to inhabit and survive vastly diverse environments. This enormous adaptive capacity depend on their ability to perceive cues from the micro-environment and process this information accordingly to mount appropriate metabolic responses and ultimately sustain homeostasis.
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Bacteria are able to inhabit and survive vastly diverse environments. This enormous adaptive capacity depend on their ability to perceive cues from the micro-environment and process this information accordingly to mount appropriate metabolic responses and ultimately sustain homeostasis.
openaire +2 more sources
Networking with protein kinases
Current Biology, 1993It is taken for granted nowadays that extracellular signals are amplified and transduced inside cells by protein kinase cascades. Hundreds of different protein kinases have already been identified and the rate of discovery of new kinases shows no sign of slowing. Until recently, however, relatively little was known about how all these different protein
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2011
Major progress has been made in unravelling of regulatory mechanisms in eukaryotic cells. Modification of target protein properties by reversible phosphorylation events has been found to be one of the most prominent cellular control processes in all organisms.
Nico Dissmeyer, Arp Schnittger
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Major progress has been made in unravelling of regulatory mechanisms in eukaryotic cells. Modification of target protein properties by reversible phosphorylation events has been found to be one of the most prominent cellular control processes in all organisms.
Nico Dissmeyer, Arp Schnittger
openaire +3 more sources
Beyond PI3Ks: targeting phosphoinositide kinases in disease
Nature Reviews Drug Discovery, 2023Joanna Triscott +2 more
exaly
Protein kinase C: A memory kinase?
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1997openaire +3 more sources
Cell cycle kinases as therapeutic targets for cancer
Nature Reviews Drug Discovery, 2009Antonio Giordano
exaly
The nuts and bolts of AGC protein kinases
Nature Reviews Molecular Cell Biology, 2010David Komander, Dario R Alessi
exaly