Results 301 to 310 of about 750,523 (310)
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Molecular and Biochemical Parasitology, 2007
The C-terminal "CaaX"-motif-containing proteins usually undergo three sequential post-translational processing steps: (1) attachment of a prenyl group to the cysteine residue; (2) proteolytic removal of the last three amino acids "aaX"; (3) methyl esterification of the exposed alpha-carboxyl group of the prenyl-cysteine residue.
James G. Bollinger +7 more
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The C-terminal "CaaX"-motif-containing proteins usually undergo three sequential post-translational processing steps: (1) attachment of a prenyl group to the cysteine residue; (2) proteolytic removal of the last three amino acids "aaX"; (3) methyl esterification of the exposed alpha-carboxyl group of the prenyl-cysteine residue.
James G. Bollinger +7 more
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Engineering Post-Translational Processing of Recombinant Proteins Produced in Insect Cell Culture
2000A number of host organisms are used today to facilitate the production of recombinant proteins. Recombinant proteins are produced in cultures derived from both prokaryotic and eukaryotic sources. The proteins obtained from these sources are used in a wide range of applications including diagnostics, structure-function studies, therapeutics, and ...
E. Ailor, M. J. Betenbaugh
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Biological Psychiatry, 1989
236 Alzheimer’s disease (AD) is characterized by extensive cholinergic denervation in both cortex and hippocampus. However, cholinergic therapies are of limited value. We investigated choline@ mechanisms in hippocampus which was denervated by a fimbriafomix lesion. Denervated pyramidal cells were found to be hypersensitive to carbachol, responding to a
John P. Anderson +3 more
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236 Alzheimer’s disease (AD) is characterized by extensive cholinergic denervation in both cortex and hippocampus. However, cholinergic therapies are of limited value. We investigated choline@ mechanisms in hippocampus which was denervated by a fimbriafomix lesion. Denervated pyramidal cells were found to be hypersensitive to carbachol, responding to a
John P. Anderson +3 more
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Post-Translational Processing of Surfactant Protein-C Proprotein
American Journal of Respiratory Cell and Molecular Biology, 2001Rat surfactant protein (SP)-C is a 3.7-kD hydrophobic lung-specific protein generated from proteolytic processing of a 21-kD propeptide (SP-C(21)). We have demonstrated that initial post-translational processing of SP-C(21) involves two cleavages of the COOH-terminus (Beers and colleagues, J. Biol. Chem. 1994;269:20,318--20,328).
Giuseppe G. Pietra +6 more
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Post-translational processing of ras proteins
Biochemical Society Transactions, 1989openaire +3 more sources
Post-translational processing and subcellular localization of the Ras-related Rap2 protein.
Oncogene, 1991The ras-related rap2 gene encodes a 21 kDa GTP-binding protein that exhibits many structural similarities with Ras proteins. In particular, it contains a C-terminal CAAX sequence (C, cysteine; A, aliphatic residue; X, any amino acid) which has been shown to direct the post-translational modifications responsible for membrane binding of Ras proteins and
F, Béranger +2 more
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Annals of the New York Academy of Sciences, 1980
Robert C. Jackson, Günter Blobel
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Robert C. Jackson, Günter Blobel
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Pepsinogen C Is a Candidate Protease for Post-Translational Processing of Surfactant Protein C.
D106. SURFACTANT AND COLLECTINS STRUCTURE AND FUNCTION: INSIGHTS INTO DISEASE MECHANISMS, 2009Surafel Mulugeta +3 more
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Post-translational control of the amyloid β-protein precursor processing
1995openaire +1 more source