Results 191 to 200 of about 142,215 (332)

Structured DNA promotes phosphorylation of p53 by DNA‐dependent protein kinase at serine 9 and threonine 18 [PDF]

, 2004
Sébastien Soubeyrand, Caroline Schild‐Poulter, Robert J.G. Haché   +2 more
openalex   +1 more source

Discovering new hub genes of dilated cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu, Yu Han, Jing‐Yu Yang, De‐Ping Wang, Li‐Juan Gao, Teng Sun, Yan‐Lin Feng, Zhong‐Mei He, Bin Zhou, Ji‐Min Cao   +9 more
wiley   +1 more source

Targeting NEK Kinases in Gastrointestinal Cancers: Insights into Gene Expression, Function, and Inhibitors. [PDF]

Int J Mol Sci
Chen L, Lu H, Ballout F, El-Rifai W, Chen Z, Gokulan RC, McDonald OG, Peng D.   +7 more
europepmc   +1 more source

Regulation and Function of the Calcium/Calmodulin-dependent Protein Kinase IV/Protein Serine/Threonine Phosphatase 2A Signaling Complex [PDF]

, 2004
Kristin A. Anderson, Pamela Noeldner, Kelie Reece, Brian E. Wadzinski, Anthony R. Means   +4 more
openalex   +1 more source

PAK3 pathogenic variant associated with sleep‐related hypermotor epilepsy in a family with parental mosaicism

Epilepsia Open, EarlyView.
Abstract Protein‐activated kinases mediate spine morphogenesis and synaptic plasticity. PAK3 is part of the p21‐activated kinases (PAKs) family of Ras‐signaling serine/threonine kinases. Pathogenic variants in the X‐linked gene PAK3 have been described in patients with neurodevelopmental syndromes.
Antonio Gambardella, Yu‐Chi Liu, Mark F. Bennett, Timothy E. Green, John A. Damiano, Francesco Fortunato, Matthew J. Coleman, Jacqueline Cherfils, Jean‐Vianney Barnier, Jozef Gecz, Melanie Bahlo, Samuel F. Berkovic, Michael S. Hildebrand   +12 more
wiley   +1 more source

Revealing the contribution of GbPR10.5D1 to resistance against Verticillium dahliae and its regulation for structural defense and immune signaling

The Plant Genome, Volume 15, Issue 4, December 2022., 2022
Abstract As an important family of pathogenesis‐related (PR) proteins, the functional diversification and roles of PR10s in biotic stress have been well documented. However, the molecular basis of PR10s in plant defense responses against pathogens remains to be further understood.
Jin Guo, Peihua Cao, Leitian Yuan, Guixian Xia, Huanyang Zhang, Jing Li, Fuxin Wang   +6 more
wiley   +1 more source

Molecular Recognition of Diaryl Ureas in Their Targeted Proteins-A Data Mining and Quantum Chemical Study. [PDF]

Molecules
Aljohani MS, Hu X.
europepmc   +1 more source

Positive Regulation of IκB Kinase Signaling by Protein Serine/Threonine Phosphatase 2A [PDF]

, 2005
Arlene E. Kray, Robert S. Carter, Kevin N. Pennington, Rey J. Gomez, Laura E. Sanders, Joan M. Llanes, Wasif N. Khan, Dean W. Ballard, Brian E. Wadzinski   +8 more
openalex   +1 more source

Non‐cytopathic bovine viral diarrhoea virus 2 induces autophagy to enhance its replication

Veterinary Medicine and Science, Volume 9, Issue 1, Page 405-416, January 2023., 2023
Ncp BVDV2 infection induced autophagy in MDBK cells via anti‐apoptosis and PKR suppression. Autophagy may play a role in establishing persistent infection caused by ncp BVDV. Abstract Background Bovine viral diarrhoea virus (BVDV) is an important viral pathogen that has an economic impact on the livestock industry worldwide.
Seung‐Uk Shin, Du‐Gyeong Han, Hyung‐Chul Cho, Eun‐Mi Kim, Kyoung‐Seong Choi   +4 more
wiley   +1 more source

Temporal characterisation and electrophysiological implications of TBI-induced serine/threonine kinase activity in mouse cortex. [PDF]

Cell Mol Life Sci
Celine G, Thomas M.
europepmc   +1 more source