Results 191 to 200 of about 209,848 (307)

Serine/Threonine-Protein Kinase ATR [PDF]

, 2020
openaire   +1 more source

Asiatic Acid Ameliorates MNNG‐Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis

Phytotherapy Research, EarlyView.
ABSTRACT Chronic atrophic gastritis (CAG), a widespread gastrointestinal condition, is widely acknowledged as a precursor to gastric cancer (GC). The incidence of CAG has been steadily increasing, yet effective pharmacological interventions remain unavailable. Asiatic acid (AA), a bioactive triterpenoid isolated from Centella asiatica, has demonstrated
Feifei Zhou, Cuiyu Zhu, Wanwan Yuan, Wenkun Peng, Qianqian Xu, Hongli Yang, Ruofan Cao, Ben Wang, Meiqian Wang, Hongwei Xu   +9 more
wiley   +1 more source

Spatial phosphoproteomics reveals regional phosphorylation features in liver cirrhosis progression. [PDF]

J Transl Med
Wu M, Tao H, Chen H, Yan Q, Zou Y, Zhou L, Xu T, Zheng X, Wen C, Zhang S, Yang R, Wang X, Dai Y.   +12 more
europepmc   +1 more source

Serine/Threonine-Protein Kinase ICK [PDF]

, 2020
openaire   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

Phospho-Proteomics Identifies D-Group MAP Kinases as Substrates of the <i>Arabidopsis</i> Tyrosine Phosphatase RLPH2. [PDF]

Plant Direct
Labandera AM, Toth R, Mitchell S, Johnson JJ, Kurucz B, Puyaubert J, Baudouin E, Uhrig RG, Moorhead GB.   +8 more
europepmc   +1 more source

Serine/Threonine-Protein Kinase 36 [PDF]

, 2020
openaire   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Dual Phosphorylation of Thr175 and Ser176 Is Essential for SnRK1α1 Activation. [PDF]

Physiol Plant
Ávila A, López A, Cervantes J, Rodríguez-Sotres R, Martínez-Barajas E, Coello P.   +5 more
europepmc   +1 more source

Serine/Threonine-Protein Kinase LMTK2 [PDF]

, 2020
openaire   +1 more source