Results 311 to 320 of about 191,213 (357)

Serine/threonine protein kinases

Current Opinion in Neurobiology, 1992
Signal transduction in the nervous system is heavily dependent on the three multifunctional serine/threonine protein kinases, PKA, PKC, and CaM-KII. Recent studies have furthered our understanding of how the multiple isoforms of these kinases and their subcellular localizations, regulatory properties, and substrate determinants are important for the ...
J D, Scott, T R, Soderling
openaire   +2 more sources

Serine/threonine protein kinases in Drosophila

Trends in Genetics, 1990
The study of serine/threonine kinases in Drosophila is coming of age. Recently several kinases have been identified and their role in cell determination has been established. This review discusses these recent findings and describes the potential for genetic analyses of kinase activity and signal transduction.
E, Siegfried, L, Ambrosio, N, Perrimon
openaire   +2 more sources

Serine/Threonine Protein Kinases and Apoptosis

Experimental Cell Research, 2000
Over the past decade, our understanding of apoptosis, or programmed cell death, has increased greatly, with the identification of some of the major components of the apoptotic programme and the processes regulating their activation. Although apoptosis is an intrinsic process present in all cells, it can be regulated by extrinsic factors, including ...
T G, Cross, D, Scheel-Toellner, N V, Henriquez, E, Deacon, M, Salmon, J M, Lord   +5 more
openaire   +2 more sources

Serine-Threonine Protein Kinases of Cyanobacteria

Biochemistry (Moscow)
Protein phosphorylation is a pivotal mechanism for signal transduction, regulation of biochemical processes essential for reproduction, growth, and adaptation of organisms to changing conditions. Bacteria, which emerged more than 3.5 billion years ago, faced the need to adapt to a variety of ecological niches from the very beginning of their existence.
Anna A, Zorina, Dmitry A, Los, Oleg I, Klychnikov   +2 more
openaire   +2 more sources

Protein Serine-Threonine Kinases

1992
Abstract In nature, a broad range of proteins become modified via the covalent bonding of phosphate to nucleophilic functional groups located on the side-chains of their constituent amino acids. Although numerous amino acids can be modified in this way, by far the most widespread and quantitatively significant phosphorylation events take
Peter J Kennelly, Arthur M Edelman
openaire   +1 more source

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

Cell, 1991
T. Boulton, S. Nye, D. Robbins, N. Ip, Elizabeth Radzlejewska, S. Morgenbesser, R. DePinho, N. Panayotatos, M. Cobb, G. Yancopoulos   +9 more
semanticscholar   +1 more source

Targeting ERK1/2 protein-serine/threonine kinases in human cancers.

Pharmacological Research, 2019
R. Roskoski
semanticscholar   +1 more source

Targeting oncogenic Raf protein-serine/threonine kinases in human cancers.

Pharmacological Research, 2018
R. Roskoski
semanticscholar   +1 more source

PLANT PROTEIN SERINE/THREONINE KINASES: Classification and Functions.

Annual Review of Plant Physiology and Plant Molecular Biology, 1999
D. Hardie
semanticscholar   +1 more source

Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism

Journal of Pineal Research, 2014
Yun Tian, Y. Yabuki, S. Moriguchi, K. Fukunaga, P. Mao, Ling-juan Hong, Ying-Mei Lu, Rui Wang, M. Ahmed, Mei‐hua Liao, Ji-yun Huang, Rui‐Ting Zhang, Tian-yi Zhou, Sen Long, F. Han   +14 more
semanticscholar   +1 more source