Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations. [PDF]
Niebrügge N+3 more
europepmc +1 more source
A Model for the Chemical Interactions of Adenosine 3':5'-Monophosphate with the R Subunit of Protein Kinase Type I. Refinement of the Cyclic Phosphate Binding moiety of Protein Kinase Type I [PDF]
Bernd Jastorff+2 more
openalex +1 more source
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua+9 more
wiley +1 more source
The Long-Term Immunity of a Microneedle Array Patch of a SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice. [PDF]
Kim E+11 more
europepmc +1 more source
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
wiley +1 more source
Finerenone Alleviates Over-Activation of Complement C5a-C5aR1 Axis of Macrophages by Regulating G Protein Subunit Alpha i2 to Improve Diabetic Nephropathy. [PDF]
Li ZH+5 more
europepmc +1 more source
Identification of G protein subunit alpha i2 as a promising therapeutic target of hepatocellular carcinoma. [PDF]
Chen M+5 more
europepmc +1 more source
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang+25 more
wiley +1 more source
Safety and immunogenicity of SARS-CoV-2 protein subunit recombinant vaccine (Indovac®) in healthy populations aged 18 years and above in Indonesia: A phase I, observer-blind, randomized, controlled study. [PDF]
Nency YM+14 more
europepmc +1 more source