Results 201 to 210 of about 895,431 (308)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infection. [PDF]

EBioMedicine
Wørzner K, Schmidt ST, Zimmermann J, Tami A, Polacek C, Fernandez-Antunez C, Hartmann KT, Jensen RF, Hansen JS, Illigen K, Isling LK, Erbs G, Jungersen G, Rosenkrands I, Offersgaard A, Gottwein J, Holmbeck K, Jensen HE, Ramirez S, Follmann F, Bukh J, Pedersen GK.   +21 more
europepmc   +1 more source

The NusA and NusG proteins of Escherichia coli increase the in vitro readthrough frequency of a transcriptional attenuator preceding the gene for the beta subunit of RNA polymerase.

, 1992
Thomas Linn, Jack Greenblatt
openalex   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

G protein subunit alpha i2's pivotal role in angiogenesis. [PDF]

Theranostics
Bai CW, Lu L, Zhang JN, Zhou C, Ni YC, Li KR, Yao J, Zhou XZ, Lan CG, Cao C.   +9 more
europepmc   +1 more source

cholera Toxin B Subunit-Diabetes Autoantigen Fusion Proteins Modulate Dendritic Cell Function and T Cell Morphogenesis

, 2011
Oludare Odumosu
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Circular RNA pappalysin-1 enhances glycolysis via microRNA-656-3p targeting G-protein subunit gamma-5 to promote colon cancer progression. [PDF]

Clinics (Sao Paulo)
Cai A, Ye H, Lin Y, Li J, Fang D, Pan Z, Li Z, Luo G, Huang Y, Lai C.   +9 more
europepmc   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein, AIC2B is a component of the high affinity interleukin-5 receptor.

, 1991
Satoshi Τακακι, Seiji Mita, Toshio Kitamura, Shin Yonehara, Naoto Yamaguchi, A Tominaga, Atsushi Miyajima, Kiyoshi Takatsu   +7 more
openalex   +2 more sources