Results 111 to 120 of about 6,757,592 (330)

Short-Chain Alkanethiol Coating for Small-Size Gold Nanoparticles Supporting Protein Stability

open access: yesMagnetochemistry, 2017
The application of gold nanoparticles (AuNPs) is emerging in many fields, raising the need for a systematic investigation on their safety. In particular, for biomedical purposes, a relevant issue are certainly AuNP interactions with biomolecules, among ...
Cristina Cantarutti   +7 more
doaj   +1 more source

Two State Behavior in a Solvable Model of $\beta$-hairpin folding

open access: yes, 1999
Understanding the mechanism of protein secondary structure formation is an essential part of protein-folding puzzle. Here we describe a simple model for the formation of the $\beta$-hairpin, motivated by the fact that folding of a $\beta$-hairpin ...
A. Finkelstein   +19 more
core   +1 more source

LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models

open access: yesAdvanced Functional Materials, EarlyView.
This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran   +5 more
wiley   +1 more source

N-Acetylaspartate Is an Important Brain Osmolyte

open access: yesBiomolecules, 2020
Most of the human diseases related to various proteopathies are confined to the brain, which leads to the development of various forms of neurological disorders.
Marina Warepam   +5 more
doaj   +1 more source

Unfolding and Refolding of Protein by a Combination of Ionic and Nonionic Surfactants

open access: yesACS Omega, 2018
The interaction of protein and surfactant yields protein–surfactant complexes which have a wide range of applications in the cosmetics, foods, and pharmaceutical industries among others.
D. Saha   +3 more
semanticscholar   +1 more source

Structure Formation in Butterfly Scales: Interplay of Genetic Control, Mechanical Instabilities, and Dynamic Material Properties

open access: yesAdvanced Functional Materials, EarlyView.
Butterfly wing scales are intricate cuticular functional nanosctructures. This perspective suggests that spatially varying material properties, cytoskeletal constraints, and growth‐driven mechanical instabilities shape the resulting nanoscale architectures created from single cells.
Anupama Prakash   +10 more
wiley   +1 more source

Antibody Aggregation: Insights from Sequence and Structure

open access: yesAntibodies, 2016
Monoclonal antibodies (mAbs) are the fastest-growing biological therapeutics with important applications ranging from cancers, autoimmunity diseases and metabolic disorders to emerging infectious diseases.
Wei Li   +5 more
doaj   +1 more source

Mechanical folding and unfolding of the redox protein Flavodoxin [PDF]

open access: yes, 2015
Màster Oficial en Física Avançada. Facultat de Física, Universitat de Barcelona, Curs: 2015, Tutors: Felix Ritort i Anna AlemanyWe investigate the unfolding and folding processes of redox protein Flavodoxin under the action of mechanical forces at the ...
Sanmartí, Enric
core  

Effects of Eye-phase in DNA unzipping

open access: yes, 2006
The onset of an "eye-phase" and its role during the DNA unzipping is studied when a force is applied to the interior of the chain. The directionality of the hydrogen bond introduced here shows oscillations in force-extension curve similar to a "saw-tooth"
A. J. Guttmann   +8 more
core   +1 more source

The Terminal Domains of Collagen‐Like Silk Direct Molecular Interactions and Liquid–Liquid Phase Separation‐Mediated Material Assembly

open access: yesAdvanced Functional Materials, EarlyView.
Terminal domains of recombinant collagen‐like silk regulate hierarchical self‐assembly across molecular and material scales. We show that terminal domains of collagen‐like silk enhance triple‐helix stability and drive liquid–liquid phase separation, enabling reversible formation of fibers and self‐healing films.
Mengjie Shen   +5 more
wiley   +1 more source

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