Results 271 to 280 of about 6,757,592 (330)

Identification of B cell epitopes enhanced by protein unfolding and aggregation.

open access: yesMol Immunol, 2019
Eyes TJ   +7 more
europepmc   +1 more source

Mechanisms of change in gel water-holding capacity of myofibrillar proteins affected by lipid oxidation: The role of protein unfolding and cross-linking.

Food Chemistry, 2020
This work explored the effects of protein unfolding and cross-linking induced by lipid oxidation (linoleic acid, OLA) on the gel water-holding capacity (WHC) of beef myofibrillar proteins (MP).
Y. Jiang   +6 more
semanticscholar   +1 more source

Modulated scanning fluorimetry can quickly assess thermal protein unfolding reversibility in microvolume samples.

Molecular Pharmaceutics, 2020
Determining the temperature at which the thermal unfolding of a protein starts becoming irreversible is relevant for many areas of protein research. Until now, published methods cannot determine, within a reasonable timeframe and with moderate sample ...
Hristo L. Svilenov   +3 more
semanticscholar   +1 more source

Nanopatterning by protein unfolding

Soft Matter, 2008
Molecular layers patterned on the nanoscale, with long-range order properties extending over the microscopic scale, have been obtained upon adsorption of commonly available proteins onto the hydrophobic and long-range ordered surface of pyrolytic graphite (HOPG).
SVALDO LANERO T.   +5 more
openaire   +3 more sources

Protein Unfolding Through Nanopores

Protein & Peptide Letters, 2014
In this mini-review we introduce and discuss a new method, at single molecule level, to study the protein folding and protein stability, with a nanopore coupled to an electric detection. Proteins unfolded or partially folded passing through one channel submitted to an electric field, in the presence of salt solution, induce different detectable ...
Oukhaled, Abdelghani   +5 more
openaire   +3 more sources

Natively unfolded proteins

Current Opinion in Structural Biology, 2005
It is now clear that a significant fraction of eukaryotic genomes encode proteins with substantial regions of disordered structure. In spite of the lack of structure, these proteins nevertheless are functional; many are involved in critical steps of the cell cycle and regulatory processes.
openaire   +2 more sources

Protein Unfolding in Cardiomyopathies

Heart Failure Clinics, 2005
For many years, protein misfolding was the basis for biochemical and biophysical studies in vitro or in microorganisms such as yeast. Recently, clinically related studies are merging the evidence collected from microorganisms with human diseases. Thus, a growing body of evidence is accumulating that identifies defects in protein folding or protein ...
GORZA, LUISA, DEL MONTE F.
openaire   +3 more sources

Pulling apart protein unfolding

Science, 2017
Protein Folding Elucidating the details of how complex proteins fold is a longstanding challenge. Key insights into the unfolding pathways of diverse proteins have come from single-molecule force spectroscopy (SMFS) experiments in which proteins are literally pulled apart. Yu et al.
openaire   +2 more sources

Sonication-induced unfolding proteins

Journal of Theoretical Biology, 2012
The methodology of predicting sonication-induced unfolding proteins (SUP) is presented in this study. The methodology bases on: (a) simulation of SUP by the excessive deviations of protein domains in regime of damped forced vibrations caused by critical level of involved acoustic energy, which is associated with temperature rise and acoustic pressure; (
openaire   +3 more sources

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