Results 121 to 130 of about 162,405 (296)
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To examine how different antiphospholipid antibody (aPL) profiles influence placental‐mediated adverse pregnancy outcomes (APOs) in women with systemic lupus erythematosus (SLE). Methods This retrospective cohort study included 245 pregnant women with SLE and 490 controls from a single center.
Meng Jiang +4 more
wiley +1 more source
Persistent proteinuria among a cohort of Nigerian children with sickle cell anaemia.
PLoS ONEBackgroundPersistent proteinuria is an early and modifiable marker of kidney damage. Although Nigeria has the highest burden of sickle cell anaemia (SCA) globally, the prevalence of proteinuria is unknown largely because many of the studies only ...
Angela Esohe Adeoti-Lawani +3 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To describe the use of the WOICE tool for assessing non‐severe maternal morbidities among pregnant and postpartum women with hypertensive disorders. Methods Secondary analysis of a previously published cross‐sectional study performed in Brazil, with the inclusion of women with hypertensive disorders (pre‐eclampsia, chronic ...
Stephanie Pabón Lozano +6 more
wiley +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Multi‐omics–driven precision medicine
iMeta, EarlyView.Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Scientific ReportsProteinuria is an important risk factor for cardiovascular disease (CVD) and acts as a surrogate marker of renal damage. This study aimed to determine the association between changes in proteinuria and the occurrence of CVD.
Ho Geol Woo, Moo-Seok Park, Tae-Jin Song
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1490-1491, April 2025.
Özant Helvacı +4 more
wiley +1 more source
Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
iNew Medicine, EarlyView.This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
wiley +1 more source