Results 201 to 210 of about 331,596 (261)

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Computational proteomics to enhance personalized treatment of COVID-19 and Long COVID. [PDF]

Clin Proteomics
Sahu D, Van Nynatten LR, Tweddell D, Daley M, Fraser DD.   +4 more
europepmc   +1 more source

Proteomic signatures of early retinal neurodegeneration in type 2 diabetes mellitus. [PDF]

PLoS Med
Li H, Zhu Z, Yang S, Cheng W, Tan S, Xin Z, Zhang L, Zhu Z, Chen S, Huang W, Wang W.   +10 more
europepmc   +1 more source

Correction to 'Integrating transcriptomics and proteomics to assess antisense oligonucleotide safety and efficacy: a time-resolved approach'. [PDF]

NAR Mol Med
europepmc   +1 more source

A cysteine reactive chloroalkane probe enables HaloTag ligation for downstream chemical proteomics analysis. [PDF]

RSC Chem Biol
Abanti RR, Wu D, Kielkowski P.
europepmc   +1 more source

Harnessing Proteogenomics to Advance Precision Oncology: From Melanoma and Hepatocellular Carcinoma Perspective. [PDF]

Curr Oncol Rep
Olagunju AS, Babalola AD, Najophe SE, Farodoye OM, Otenaike TA, Godswill US, Teibo JO.   +6 more
europepmc   +1 more source