Results 181 to 190 of about 218,532 (388)

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

open access: yesBrain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery   +17 more
wiley   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

open access: yesBritish Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk   +2 more
wiley   +1 more source

Comparación de diferentes métodos para identificar las especies del género Proteus Comparison of different methods in order to identify Proteus spp

open access: yesRevista Argentina de Microbiología, 2006
Los objetivos de este trabajo fueron: a) identificar a nivel de especie aislamientos de Proteus siguiendo la combinación de los esquemas de Farmer y O'Hara; b) determinar la utilidad del sistema comercial API 20E y de un esquema reducido de pruebas (agar
S. T. Castro   +10 more
doaj  

Pericarditis caused by Proteus mirabilis in sheep [PDF]

open access: gold, 2023
Abolfazl Najd Ghahremani   +3 more
openalex   +1 more source

Orthotopic Esophageal Cancer Xenograft Model in Immunosuppressed Microminipigs for Near‐Infrared Fluorescence Endoscopy

open access: yesCancer Science, EarlyView.
We report the first successful orthotopic engraftment of human esophageal squamous cell carcinoma in immunosuppressed microminipigs and demonstrate high‐contrast near‐infrared fluorescence endoscopic detection using EGFR‐targeted cetuximab. This large‐animal model bridges preclinical imaging research and future clinical translation in esophageal cancer.
Takanori Miyake   +14 more
wiley   +1 more source

Morphology‐based phylogeny of longhorn beetles (Coleoptera, Cerambycidae) aligns with phylogenomics and informs higher‐level systematics

open access: yesCladistics, EarlyView.
Abstract We present a morphology‐based backbone phylogeny of Cerambycidae beetles inferred by parsimony analyses using 77 adult characters scored for 101 species. This phylogeny is largely consistent with recent phylogenomic studies regarding key placements (e.g., Parandrini stat. rev. within Prioninae, Necydalini stat. rev.
Burcu Şabanoğlu Şimşek   +2 more
wiley   +1 more source

Representation of obligate groundwater‐dwelling copepod diversity in European protected areas

open access: yesConservation Biology, EarlyView.
Abstract Groundwaters sustain diverse surface ecosystems and are populated by metazoan species, mostly invertebrates, that provide fundamental ecological functions and are often of prominent conservation value due to narrow endemism and high phylogenetic rarity.
Francesco Cerasoli   +7 more
wiley   +1 more source

Quantum Chemistry-Driven Molecular Inverse Design of Stable Isomers with Data-Free Reinforcement Learning. [PDF]

open access: yesJ Chem Theory Comput
Calcagno F   +5 more
europepmc   +1 more source

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