Correction: McSorley, J.C. Analysis of ESAC-Net/EARS-Net Data from 29 EEA Countries for Spatiotemporal Associations Between Antimicrobial Use and Resistance-Implications for Antimicrobial Stewardship? <i>Antibiotics</i> 2025, <i>14</i>, 399. [PDF]
McSorley JC.
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Copper Overload Affects α‐Synuclein Clearance Mechanisms in a Parkinson's Disease In Vitro Model
This study reveals that copper overload disrupts neuronal protein clearance, leading to the accumulation of α‐synuclein and its phosphorylated form (p‐S129). By blocking autophagy and impairing the ubiquitin–proteasome system, copper promotes toxic aggregation in dopaminergic cells.
Debora Musarò +4 more
wiley +1 more source
Commissioning and clinical implementation of Monaco treatment planning system on a compact pencil beam scanning proton therapy system. [PDF]
Xu X +13 more
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Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng +19 more
wiley +1 more source
Antibiogram of isolated bacteria and overview of resistome and virulome of multi-drug resistant Escherichia coli from ready-to-eat foods vended in Lagos, Nigeria. [PDF]
Makinde OM +4 more
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ABSTRACT Objective We aimed to evaluate medical decisions regarding urinary tract infection (UTI), describe associated microorganisms, and assess potential risk factors for percutaneous nephrostomy‐related UTI (UTI‐PN). Methods Oncological patients who underwent percutaneous nephrostomy (PN) were included. We assessed percutaneous nephrostomy procedure‐
Jeferson Rodrigo Zanon +3 more
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Distribution and Drug-Resistance Analysis of Uropathogens in Urinary Tract Infections. [PDF]
Wu W, Wu Q, Zhong W, Han L.
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ABSTRACT The central nervous system (CNS) is the most common site of extramedullary relapse in acute lymphoblastic leukemia (ALL). However, the diagnosis may be challenging due to its protean manifestations. A 64‐year‐old male reported right‐sided hearing loss with intermittent bilateral occipitotemporal headaches during a clinic follow‐up for Ph + B ...
Jun Yen Ng +3 more
wiley +1 more source
Prevalence and phenotypic characterization of carbapenem resistance in multidrug-resistant Gram-negative bacteria across selected healthcare facilities in the United Arab Emirates: a retrospective study. [PDF]
Aljaede RAM +8 more
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