Results 11 to 20 of about 86,742 (68)

New Genomic Signals Underlying the Emergence of Human Proto-Genes

open access: yesbioRxiv, 2022
De novo genes are novel genes which emerge from non-coding DNA. Until now, little is known about de novo genes properties, correlated to their age and mechanisms of emergence.
Anne-Catherine Grandchamp   +3 more
semanticscholar   +1 more source

Cryptogamic ground covers as analogues for early terrestrial biospheres: Initiation and evolution of biologically mediated proto‐soils

open access: yesGeobiology, 2021
Modern cryptogamic ground covers (CGCs), comprising assemblages of bryophytes (hornworts, liverworts, mosses), fungi, bacteria, lichens and algae, are thought to resemble early divergent terrestrial communities.
R. Mitchell   +5 more
semanticscholar   +1 more source

Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells

open access: yesInternational Journal of Molecular Sciences, 2021
In principle, an oncogene is a cellular gene (proto-oncogene) that is dysfunctional, due to mutation and fusion with another gene or overexpression. Generally, oncogenes are viewed as deregulating cell proliferation or suppressing apoptosis in driving ...
Geoffrey Brown
semanticscholar   +1 more source

The Oligo–Miocene closure of the Tethys Ocean and evolution of the proto-Mediterranean Sea

open access: yesScientific Reports, 2020
The tectonically driven Cenozoic closure of the Tethys Ocean invoked a significant reorganization of oceanic circulation and climate patterns on a global scale. This process culminated between the Mid Oligocene and Late Miocene, although its exact timing
A. Torfstein, J. Steinberg
semanticscholar   +1 more source

An Experimental Evaluation of the Proto-MATE: A Novel Ergonomic Upper-Limb Exoskeleton to Reduce Workers' Physical Strain

open access: yesIEEE robotics & automation magazine, 2020
Wearable passive upper-limb exoskeletons have been proposed and commercialized as tools to improve the ergonomics of workers in repetitive or physically demanding tasks.
I. Pacifico   +12 more
semanticscholar   +1 more source

Mutually stabilizing interactions between proto-peptides and RNA

open access: yesNature Communications, 2020
The close synergy between peptides and nucleic acids in current biology is suggestive of a functional co-evolution between the two polymers. Here we show that cationic proto-peptides (depsipeptides and polyesters), either produced as mixtures from ...
Moran Frenkel-Pinter   +9 more
semanticscholar   +1 more source

Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy

open access: yesNature Communications, 2020
Increased lipogenesis has been linked to an increased cancer risk and poor prognosis; however, the underlying mechanisms remain obscure. Here we show that phosphatidic acid phosphatase (PAP) lipin-1, which generates diglyceride precursors necessary for ...
Lintao Song   +17 more
semanticscholar   +1 more source

Thematic proto-roles and argument selection

open access: yes, 1991
As a novel attack on the perennially vexing questions of the theoretical status of thematic roles and the inventory of possible roles, this paper defends a strategy of basing accounts of roles on more unified domains of linguistic data than have been ...
David R. Dowty
semanticscholar   +1 more source

Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts

open access: yesNature Communications, 2020
Photosynthetic CO2 fixation in plants is limited by the inefficiency of the CO2-assimilating enzyme Rubisco. In most eukaryotic algae, Rubisco aggregates within a microcompartment known as the pyrenoid, in association with a CO2-concentrating mechanism ...
Nicky Atkinson   +3 more
semanticscholar   +1 more source

Paleogene evolution and demise of the proto‐Paratethys Sea in Central Asia (Tarim and Tajik basins): Role of intensified tectonic activity at ca. 41 Ma

open access: yesBasin Research, 2019
The proto‐Paratethys Sea covered a vast area extending from the Mediterranean Tethys to the Tarim Basin in western China during Cretaceous and early Paleogene.
M. Kaya   +14 more
semanticscholar   +1 more source

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