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Expression and Function of the c-kit Proto-Oncogene Protein in Mouse Sperm

open access: closedThe Journal of Urology, 1998
The presence and role of the c-kit protein were examined in mature sperm of the mouse. Monoclonal antibodies (mAbs) against the c-kit protein were used to perform immunohistochemical staining, electron microscopy studies, and Western blot analysis. The acrosomal region of both fixed and unfixed noncapacitated sperm stained with the antibodies.
H, Feng, J I, Sandlow, A, Sandra
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Proto-oncogene c-kit expression in malignant melanoma: protein loss with tumor progression.

open access: closedModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1997
The c-kit gene encodes a transmembrane receptor that has tyrosine kinase activity. c-kit plays a role in hematopoiesis, gametogenesis, and melanogenesis. c-kit is found in melanocytes, and there is evidence that expression is lost in melanoma. We studied 85 melanocytic lesions for c-kit by immunohistochemical techniques using a monoclonal antibody. The
K T, Montone   +3 more
openaire   +2 more sources
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MYB Proto-Oncogene Like 2 Promotes the Growth of Renal Carcinoma by Attenuating Endoplasmic Reticulum Stress and Activating Lipid Rafts.

Archivos españoles de urología
OBJECTIVE Renal cell carcinoma (RCC) is a typical malignant lesion of kidney with high recurrence rate and high mortality. MYB proto-oncogene-like 2 (MYBL2) is significantly expressed in cancer cells and closely linked to cancer development and poor ...
Xiaoxi Zhang   +5 more
semanticscholar   +1 more source

C-Kit Immunoreactivity in Endometrial Adenocarcinomas and Its Clinicopathologic Significance

International Journal of Gynecological Pathology, 2003
J. Scobie   +7 more
semanticscholar   +1 more source

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