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Expression and Function of the c-kit Proto-Oncogene Protein in Mouse Sperm
The presence and role of the c-kit protein were examined in mature sperm of the mouse. Monoclonal antibodies (mAbs) against the c-kit protein were used to perform immunohistochemical staining, electron microscopy studies, and Western blot analysis. The acrosomal region of both fixed and unfixed noncapacitated sperm stained with the antibodies.
H, Feng, J I, Sandlow, A, Sandra
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Proto-oncogene c-kit expression in malignant melanoma: protein loss with tumor progression.
The c-kit gene encodes a transmembrane receptor that has tyrosine kinase activity. c-kit plays a role in hematopoiesis, gametogenesis, and melanogenesis. c-kit is found in melanocytes, and there is evidence that expression is lost in melanoma. We studied 85 melanocytic lesions for c-kit by immunohistochemical techniques using a monoclonal antibody. The
K T, Montone +3 more
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Archivos españoles de urología
OBJECTIVE Renal cell carcinoma (RCC) is a typical malignant lesion of kidney with high recurrence rate and high mortality. MYB proto-oncogene-like 2 (MYBL2) is significantly expressed in cancer cells and closely linked to cancer development and poor ...
Xiaoxi Zhang +5 more
semanticscholar +1 more source
OBJECTIVE Renal cell carcinoma (RCC) is a typical malignant lesion of kidney with high recurrence rate and high mortality. MYB proto-oncogene-like 2 (MYBL2) is significantly expressed in cancer cells and closely linked to cancer development and poor ...
Xiaoxi Zhang +5 more
semanticscholar +1 more source
Coexpression of stem cell factor and its receptor c-Kit in human malignant glioma cell lines
Acta Neuropathologica, 2004M. Stanulla +3 more
semanticscholar +1 more source
C-Kit Immunoreactivity in Endometrial Adenocarcinomas and Its Clinicopathologic Significance
International Journal of Gynecological Pathology, 2003J. Scobie +7 more
semanticscholar +1 more source
The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus
Nature, 1988B. Chabot +4 more
semanticscholar +1 more source
The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene
Cell, 1988E. Geissler, Melanie A. Ryan, D. Housman
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Abstract 5482: Antileukemic activity of 2-deoxy-d-glucose in acute myeloid leukemia
, 2014C. Larrue, S. Manenti, C. Récher
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