Results 41 to 50 of about 237,568 (122)

Expression and Function of the c-kit Proto-Oncogene Protein in Mouse Sperm1 [PDF]

Biology of Reproduction, 1997
Huailiang Feng, Jay I. Sandlow, Alexander Sandra   +2 more
openaire   +1 more source

HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer [PDF]

, 2017
Homeobox (HOX) genes are conserved transcription factors which determine the anterior-posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several tumors such as lung carcinoma, neuroblastoma, glioma and colorectal cancer (CRC ...
Mansour, Mohammed A., Senga, Takeshi
core   +1 more source

Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles [PDF]

, 2019
Over 95% of pancreatic adenocarcinomas (PDACs), as well as a large fraction of other tumor types, such as colorectal adenocarcinoma, are driven by KRAS activation. However, no direct RAS inhibitors exist for cancer therapy.
Bi, Ye, Brooks, Candace, DeNardo, David G, Fields, Ryan C, Fleming, Timothy, Gillanders, William E, Goedegebuure, S Peter, Hawkins, William G, Krasnick, Bradley A, Pan, Hua, Sankpal, Narendra, Strand, Matthew S, Wetzel, Christopher, Wickline, Samuel A, Zhang, Xiuli   +14 more
core   +1 more source

Development of a method for screening short-lived proteins using green fluorescent protein. [PDF]

, 2004
We have developed a screening technology for the identification of short-lived proteins. A green fluorescent protein (GFP)-fusion cDNA library was generated for monitoring degradation kinetics. Cells expressing a subset of the GFP-cDNA expression library
Coffino, Philip, Jiang, Xin, Li, Xianqiang   +2 more
core  

Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells [PDF]

, 2000
Stem cell factor (SCF) has an important role in the proliferation, differentiation, survival, and migration of hematopoietic cells. SCF exerts its effects by binding to cKit, a receptor with intrinsic tyrosine kinase ...
Akker, E. (Emile) van den, Dijk, T.B. (Thamar) van, Lindern, M.M. (Marieke) von, Löwenberg, B. (Bob), Mano, H., Parren-Van Amelsvoort, M. (Martine)   +5 more
core   +1 more source

Molecular genetics of development studied in the transgenic mouse. [PDF]

, 1989
Gruss, P., Westphal, H.
core   +2 more sources

Synergistic antitumor effect of oroxylin A and donafenib in hepatocellular carcinoma through tumor protein p53 signaling pathway activation. [PDF]

World J Gastroenterol
Zhang MY, Sun RQ, Min Q, Zhu YQ, Qin SK, Guo QL.   +5 more
europepmc   +1 more source

c-KIT joins the TSC ToolKIT: a new driver of renal cystogenesis. [PDF]

EMBO Mol Med
Woodford MR, Bourboulia D, Mollapour M.
europepmc   +1 more source

Ponatinib confers adult human cardiomyocyte toxicity via inhibition of AKT signaling. [PDF]

Physiol Rep
Guo L, Rao R, Liu H, Zhou B.
europepmc   +1 more source

Upregulation of itchy E3 ubiquitin protein ligase contributes to endometrial cancer through promoting forkhead box P1 degradation. [PDF]

Cytojournal
Zhang YH, Yu HY, Li CF, Li JC.
europepmc   +1 more source