The epigenetic basis of hepatocellular carcinoma - mechanisms and potential directions for biomarkers and therapeutics. [PDF]
Lin HY+8 more
europepmc +1 more source
Association of SIRT6 Expression With Risk of Pneumonitis Induced by Radiotherapy in Cancer Patients
ABSTRACT Thoracic tumours represent a significant proportion of malignant cancers. While radiotherapy (RT) improves prognosis, it can also lead to side effects such as radiation‐induced pneumonitis (RP). Since SIRT6 is involved in DNA repair, energy metabolism and inflammation, this study aims to investigate the expression of SIRT6 in lymphocytes as a ...
Fengyuan Yu+14 more
wiley +1 more source
Pathogenesis and Management Strategies in Radioiodine-Refractory Differentiated Thyroid Cancer: From Molecular Mechanisms Toward Therapeutic Approaches: A Comprehensive Review. [PDF]
Voinea IA+6 more
europepmc +1 more source
Minimal Residual Disease Detection: Implications for Clinical Diagnosis and Cancer Patient Treatment
Currently, a variety of methods such as flow cytometry, polymerase chain reaction, next‐generation sequencing, and other emerging methods are used for the detection of minimal residual disease, each of which has its own unique strengths and limitations and, more importantly, promising clinical applications.
Meiling Song+10 more
wiley +1 more source
Targeted liquid biopsy for brain tumors. [PDF]
Izhar M, Ahmad Z, Moazzam M, Jader A.
europepmc +1 more source
Deep Learning in Digital Breast Tomosynthesis: Current Status, Challenges, and Future Trends
Breast cancer detection involves a combination of clinical diagnosis, pathological examination, and various imaging tests. We focus on utilizing deep learning models in digital breast tomosynthesis for diagnostic classification, lesion localization, and medical image generation.
Ruoyun Wang+12 more
wiley +1 more source
Comprehensive management of MET tyrosine kinase inhibitor-induced peripheral edema in patients with <i>MET</i>-altered non-small-cell lung cancer: a narrative review. [PDF]
Lin JX+5 more
europepmc +1 more source
Mitochondrial Transplantation: A Novel Therapeutic Approach for Treating Diseases
This article describes the roles of mitochondria in health and disease and reviews the effects of mitochondrial transplantation in disease, including restoring ATP production, attenuating oxidative stress, modulating inflammatory responses, reducing apoptosis, promoting cell repair, and exhibiting antitumor properties.
Xinglu Miao+4 more
wiley +1 more source
Alterations in Methionine Cycle and Wnt/MAPK Signaling Associated with HMBi-Induced Cashmere Growth in Goats. [PDF]
Xi M+6 more
europepmc +1 more source
Metformin combined with CB-839 specifically inhibits KRAS-mutant ovarian cancer. [PDF]
Wu H+5 more
europepmc +1 more source