Results 11 to 20 of about 4,616 (70)
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Integrative Approaches for DNA Sequence‐Controlled Functional Materials
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo +4 more
wiley +1 more source
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack +9 more
wiley +1 more source
Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li +11 more
wiley +1 more source
Nanotechnology‐Enhanced Approaches for Early Cancer Diagnosis
Conventional MRI and PET provide limited sensitivity and contrast for precise brain lesion detection. In contrast, radiolabeled nanoparticlebased PET imaging enables enhanced signal specificity and sensitivity. By integrating multifunctional nanoprobes, this platform improves multimodal imaging performance, allowing more accurate visualization of ...
Jongmoo Lee +5 more
wiley +1 more source
Bridging the Gap: How Organ‐on‐a‐Chip Technology Facilitates the Battle against Glioma
This review critically evaluates current state‐of‐the‐art in vitro glioma models especially glioma‐on‐a‐chip models based on readout capability, performance, and physiological relevance. It summarizes the key parameters and proposes a practical framework to guide researchers in selecting the most suitable preclinical models for glioma studies.
Su Liu +5 more
wiley +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding +5 more
wiley +1 more source
The Immune Microenvironment in Liver Cancer: From Analysis to Targeting
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan +5 more
wiley +1 more source
Air pollution, a major global health hazard, contributes to asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and lung cancer via four core epigenetic pathways (DNA/RNA methylation, noncoding RNAs, and histone modifications), shaping gene expression and driving disease pathogenesis.
Ruitong Zeng +6 more
wiley +1 more source

