Results 111 to 120 of about 29,629 (128)

RAS-GTP Inhibition Overcomes Acquired Resistance to KRASG12C Inhibitors Mediated by Oncogenic and Wild-Type RAS Activation in Non-Small Cell Lung Cancer. [PDF]

Cancer Res
Solanki HS, Shah H, Imbody D, Desai B, Kato R, Miroshnychenko D, Stern YE, Majumder A, Sarcar B, Xieraili A, Stewart PA, Fang B, Zhang Y, Yao J, Darville LN, Koomen JM, Rix U, Evans JW, Yang YC, Ahler E, Marusyk A, Singh M, Aronchik I, Haura EB.   +23 more
europepmc   +1 more source

Diffuse Large B-cell lymphoma in a Ras-Associated Autoimmune Leukoproliferative Disorder (RALD). [PDF]

Ann Hematol
Sun C, Zhao L, Xia J, Wang K, Zhou S, Liu L, Yang S, Cao Y, Li Z, Zhou X, Xiao S.   +10 more
europepmc   +1 more source

CRISPR knockout screens reveal JUN as the master mediator of resistance to MAPK inhibition in KRAS-mutant pancreatic cancer. [PDF]

J Exp Clin Cancer Res
Mulero-Sánchez A, Bosma A, Visuvasam B, Pouliopoulou N, van de Ven M, Proost N, Boeije M, Lieftink C, Beijersbergen R, Bernards R, Mainardi S.   +10 more
europepmc   +1 more source

Phase II single-arm study of palbociclib and cetuximab in anti-EGFR naïve patients with KRAS/NRAS/BRAF wild-type, metastatic colorectal cancer. [PDF]

Oncologist
Sorah JD, Moore DT, Reilley MJ, Salem ME, Triglianos T, McRee AJ, Lee MS, Sanoff HK, Somasundaram AS.   +8 more
europepmc   +1 more source

Targeting KRAS G12D: Advances in Inhibitor Design. [PDF]

Thorac Cancer
Shi K, Li A.
europepmc   +1 more source

Differential effects of KRAS G-domain and hypervariable region mutants on cancer phenotypes. [PDF]

Sci Rep
de Borja JAD, Hao Lin KDJ, Mirador DAR, Ang AID, Chua SAA, Sytangco JMD, Sacdalan DL, Garcia RL.   +7 more
europepmc   +1 more source

KRAS G12C inhibitors versus chemotherapy in second line and beyond in adults with advanced or metastatic non-small cell lung cancer (NSCLC) harbouring the KRAS G12C mutation. [PDF]

Cochrane Database Syst Rev
Noordhof A, Asmara OD, de Jong K, Gijtenbeek RG, Huitema YM, van Vollenhoven FH, Venmans BJ, Hendriks L, van Geffen WH.   +8 more
europepmc   +1 more source

Denitrogenative Alkylation of K-Ras(G12D) Inhibits Oncogenic Signaling in Cancer Cells. [PDF]

J Am Chem Soc
Zheng Q, Shokat KM.
europepmc   +1 more source

Investigating incidence of RAS/RAF and PIK3CA alterations in HER2-amplified colorectal cancer: a comprehensive analysis. [PDF]

Oncologist
Cheng S, Gomez CG, Ferrell M, Giza R, Syed MP, Magge T, Gorantla V, Hsieh RW, Bao R, Singhi A, Saeed A, Sahin IH.   +11 more
europepmc   +1 more source

Advances in Targeted Therapy for Non-Small-Cell Lung Cancer: Current Progress and Future Directions. [PDF]

Int J Mol Sci
Peshin S, Takrori E, Yazji JH, Haque J, Dharia A, Mithani MS, Anum F, Asfeen U, Couch JK, Donovan M, Singal S.   +10 more
europepmc   +1 more source