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A Role for Proto-Oncogenes in Differentiation?

1986
Ever since the discovery of proto-oncogene products in the normal cell, their biological role and molecular function have been of major interest in molecular and cellular biology. To date more than 30 different c-onc genes are known which encode proteins localized in the nucleus or cytoplasm, are associated with the plasma membrane or even secreted ...
Erwin F. Wagner, Rolf Müller
openaire   +2 more sources

mos proto-oncogene function.

Ciba Foundation symposium, 1990
Maturation promoting factor (MPF) is a cytoplasmic activity that causes oocytes arrested in prophase to resume meiosis. An inactive form of MPF termed pre-MPF exists in fully grown oocytes. In Xenopus oocytes, progesterone induces maturation and pre-MPF activation. These early maturation events require protein synthesis.
Vande, Woude   +7 more
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Proto-oncogenes

Biochimie, 1987
D, Montarras, C, Pinset
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Role of proto-oncogenes in myocardial hypertrophy

The American Journal of Cardiology, 1988
A question of major clinical significance in cardiology is the nature of the signals that initiate and maintain the various types of myocardial hypertrophy, either in response to hemodynamic loading or in the absence of altered load. This review suggests that the proto-oncogene model, a concept derived from the study of cancer, can be very useful in ...
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Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Nature, 2001
L. Pasqualucci   +7 more
semanticscholar   +1 more source

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