Results 41 to 50 of about 4,339,115 (316)

A sensitive coupled enzyme assay for measuring kinase and ATPase kinetics using ADP-specific hexokinase [PDF]

open access: yes, 2020
Kinases and ATPases perform essential biological functions in metabolism and regulation. Activity of these enzymes is commonly measured by coupling ATP consumption to the synthesis of a detectable product.
McFarlane, Ciaran, Murray, James
core   +1 more source

THRIFTY—A High-throughput Single Muscle Fiber Typing Method Based on Immunofluorescence Detection [PDF]

open access: yes, 2023
Skeletal muscle consists of a mixture of fiber types with different functional and metabolic characteristics. The relative composition of these muscle fiber types has implications for muscle performance, whole-body metabolism, and health.
Oscar Horwath   +11 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Quantitative Analysis of Clot Deposition on Extracorporeal Life Support Membrane Oxygenators Using Digital and Scanning Electron Microscopy Imaging Techniques [PDF]

open access: yes, 2023
Device-induced thrombosis remains a major complication of extracorporeal life support (ECLS). To more thoroughly understand how blood components interact with the artificial surfaces of ECLS circuit components, assessment of clot deposition on these ...
Harea, George T.   +10 more
core   +1 more source

Route Selection for Multi-Hop Cognitive Radio Networks Using Reinforcement Learning: An Experimental Study

open access: yesIEEE Access, 2016
Cognitive radio (CR) enables unlicensed users to explore and exploit underutilized licensed channels (or white spaces). While multi-hop CR network has drawn significant research interest in recent years, majority work has been validated through ...
Aqeel Raza Syed   +5 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Epicutaneous Application of Mannan Induces Psoriasis-like Inflammation in an Inbred Mouse Strain [PDF]

open access: yes, 2023
Mannan from yeast induces psoriasis-like inflammation in the skin of inbred mouse strains. Limitations of available models led us to develop a new psoriasis model with a rapid disease onset, severe disease course, short duration, and a simple and easy-to-
Wu, Huimei,   +3 more
core   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

Virus-Mediated Genome Editing in Plants Using the CRISPR/Cas9 System [PDF]

open access: yes, 2019
Targeted modification of plant genomes is a powerful strategy for investigating and engineering cellular systems, paving the way for the discovery and development of important, novel agricultural traits. Cas9, an RNA-guided DNA endonuclease from the type
Mahfouz, Magdy M.   +3 more
core   +1 more source

Exercise during chemotherapy to prevent breast cancer-related cognitive decline: protocol for a pilot randomized controlled trial

open access: yesFrontiers in Cognition, 2023
BackgroundCancer-related cognitive decline (CRCD) is one of the most reported and debilitating symptoms associated with breast cancer treatment with no currently accepted treatment.
Elizabeth A. Salerno   +12 more
doaj   +1 more source

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