Results 71 to 80 of about 5,059,786 (358)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Ornament induced complications in snake bites: Revisiting the “Do it RIGHT” approach

open access: yesJournal of Family Medicine and Primary Care, 2016
Limb adorning ornaments (LAO) can exacerbate the local effects of envenoming in case of venomous snake bite. Cultural presuppositions do inhibit victims from removing symbolically/ritually important jewelry even under circumstances that might increase ...
Subhendu Mallik   +3 more
doaj   +1 more source

Efficacy of electroacupuncture with different frequencies in the treatment of chemotherapy-induced peripheral neuropathy: A study protocol for a randomized controlled trial

open access: yesFrontiers in Neurology, 2022
IntroductionChemotherapy-induced peripheral neuropathy (CIPN) is a common complication in patients with cancer during chemotherapy. It mainly leads to severe numbness of the hands and feet and causes great pain in patients.
Chao Lu   +6 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Introducing Article Processing Charges to Create a Sustainable Future

open access: yesBio-Protocol, 2022
Fanglian He   +2 more
doaj   +1 more source

Classification and Characterization of Core Grid Protocols for Global Grid Computing [PDF]

open access: yesarXiv, 2013
Grid computing has attracted many researchers over a few years, and as a result many new protocols have emerged and also evolved since its inception a decade ago. Grid protocols play major role in implementing services that facilitate coordinated resource sharing across diverse organizations.
arxiv  

Arabidopsis Protocols

open access: yes, 1998
Peer ...
Martínez-Zapater, José M.   +1 more
openaire   +2 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Analysis of the main consensus protocols of blockchain

open access: yesICT Express, 2020
Blockchain is the core technology of many cryptocurrencies. Blockchain as a distributed ledger technology has received extensive research attention. In addition to cryptography and P2P (peer-to-peer) technology, consensus protocols are also a fundamental
Shijie Zhang, Jong-Hyouk Lee
doaj  

Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial

open access: yesTrials, 2020
Objectives Zilucoplan (complement C5 inhibitor) has profound effects on inhibiting acute lung injury post COVID-19, and can promote lung repair mechanisms that lead to improvement in lung oxygenation parameters.
Jozefien Declercq   +20 more
doaj   +1 more source

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